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ProteomicshSSB1 DNA-binding is modulated by dynamic DNA-PK-mediated phosphorylation
The maintenance of genomic stability is essential for cellular viability and the prevention of diseases such as cancer. Human single-stranded DNA binding protein 1 (hSSB1) is a protein with roles in the stabilisation and restart of stalled DNA replication forks, as well as in the repair of oxidative...
ORGANISM(S): Homo sapiens (Human) 
2018-02-07 | PXD003964 | Pride
Human / hssb1 / dna-pk / ppp family phosphatase / replication stress / hydroxyurea / sciex 5600 
TranscriptomicsChip-chip from WT and Polycomb Component Kock Out Mouse ES cells for H2AZ, H3K27me3, EZH2 and Ring1B.
The essential histone variant H2A.Z localises to both active and silent chromatin sites. In embryonic stem cells (ESCs), H2A.Z is also reported to co-localise with polycomb repressive complex 2 (PRC2) at developmentally silenced genes. The mechanism of H2A.Z targeting is not clear, but a role for th...
ORGANISM(S): Mus musculus 
2012-04-15 | E-GEOD-36999 | biostudies-arrayexpress
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