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ProteomicsSARS-Cov2 coronavirus spike protein-induced apoptosis, inflammatory and oxidative stress responses in THP-1-Like-Macrophages: potential role of angiotensin converting enzyme inhibitor (perindopril)
A purified spike (S) glycoprotein for SARS-COV-2 coronavirus was used to studying its effects on THP-1 macrophages, PBMCs and HUVEC cells. The S protein mediates SARS-CoV-2 entry into cells through binding to angiotensin converting enzyme 2 (ACE2) receptors. We measured viability, intracellular cyto...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Homo sapiens (Human) 
2021-11-16 | PXD025516 | Pride
Sars-cov-2 spike protein  monocyte/macrophages  inflammation  angiotensin converting enzyme inhibitor  proteomics 
ProteomicsProteomics profiling of KAIMRC1 in comparison to MDA-MB231 and MCF-7
Proteomics characterization of KAIMRC1 cell line, a naturally immortalized breast cancer cells, is described in comparison to MCF7 and MDA-231 breast cancer cells. Quantitative proteomics analysis using the tandem mass tag (TMT) labeled technique in conjunction with phosphopeptide enrichment method ...
ORGANISM(S): Homo sapiens (Human) 
2020-06-22 | PXD017721 | Pride
Breast cancer  cell lines  tmt  proteomics  phosphoproteomics 
UnknownDiscovery of a novel potentially transforming somatic mutation in CSF2RB gene in breast cancer.
Not available
S-EPMC8607246 | biostudies-literature
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