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TranscriptomicsA piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice
We examined the construction of the piRNA system in the restricted developmental window in which methylation patterns are set during mammalian embryogenesis. We find robust expression of two Piwi family proteins, MIWI2 and MILI. Their associated piRNA profiles reveal differences from Drosophila wher...
ORGANISM(S): Mus musculus 
2008-10-01 | E-GEOD-12757 | biostudies-arrayexpress
GenomicsIdentification of maternal imprinting control regions (ICRs) in the post-implantation mouse embryo.
Genomewide DNA methylation profiles, generated by MeDIP-seq, for 8.5dpc wildtype and Dnmt3l-/+ mouse embryos were compared to identify differentially methylated regions (DMRs) that depend on the activity of the de novo DNA methyltransferase cofactor Dnmt3l in the oocyte. These DMRs were further char...
ORGANISM(S): Mus musculus 
2012-10-04 | E-GEOD-32687 | biostudies-arrayexpress
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