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Transcriptomicsc-Myc binding in HL60 cells
Analysis of technical variance of ChIP-on-Chip studies by characterization of Myc-binding in HL60 cells. Keywords: Chip-on-chip Characterization of c-Myc binding in HL60 cells. Thirteen biologically independent replicates of growing HL60 cells were subjected to ChIP with an N-terminal c-Myc antibod...
ORGANISM(S): Homo sapiens 
2010-05-17 | E-GEOD-8447 | biostudies-arrayexpress
TranscriptomicsMicro-RNAs in Adult Long-Evans (Turku/AB) Rat Liver are Refractory to 96 Hours Dioxin Treatment
Dioxin-like chemicals are well-known for their ability to upregulate expression of numerous genes via the AH receptor (AHR). However, recent transcriptomic analyses in several laboratories indicate that dioxin-like chemicals or AHR genotype itself also can downregulate levels of mRNAs encoded by nu...
ORGANISM(S): Rattus norvegicus 
2007-08-14 | E-GEOD-8469 | biostudies-arrayexpress
TranscriptomicsMicro-RNAs in Adult Rat Liver are Refractory to 19 Hours Dioxin Exposure
Dioxin-like chemicals are well-known for their ability to upregulate expression of numerous genes via the AH receptor (AHR). However, recent transcriptomic analyses in several laboratories indicate that dioxin-like chemicals or AHR genotype itself also can downregulate levels of mRNAs encoded by nu...
ORGANISM(S): Rattus norvegicus 
2007-08-15 | E-GEOD-8467 | biostudies-arrayexpress
TranscriptomicsMicro-RNAs levels in wildtype vs. Ahr-null adult mouse liver constitutively and in response to doxin treatment.
Dioxin-like chemicals are well-known for their ability to upregulate expression of numerous genes via the AH receptor (AHR). However, recent transcriptomic analyses in several laboratories indicate that dioxin-like chemicals or AHR genotype itself also can downregulate levels of mRNAs encoded by nu...
ORGANISM(S): Mus musculus 
2007-08-14 | E-GEOD-8468 | biostudies-arrayexpress
TranscriptomicsMicro-RNAs in Adult Rat Liver are Refractory to Dioxin Treatment
Dioxin-like chemicals are well-known for their ability to upregulate expression of numerous genes via the AH receptor (AHR). However, recent transcriptomic analyses in several laboratories indicate that dioxin-like chemicals or AHR genotype itself also can downregulate levels of mRNAs encoded by nu...
ORGANISM(S): Rattus norvegicus 
2007-08-15 | E-GEOD-8470 | biostudies-arrayexpress
TranscriptomicsCharacterization of technical variation in ChIP-on-chip studies
Analysis of technical variance of ChIP-on-Chip studies by characterization of Myc-binding in HL60 cells. Keywords: Chip-on-chip Fully-blocked study of technical variance in Myc-binding in HL60 cells. Two different antibodies were used to generate 6 biologically independent replicates each. Each repl...
ORGANISM(S): Homo sapiens 
2008-10-31 | E-GEOD-8448 | biostudies-arrayexpress
TranscriptomicsMicroarray Analysis of the Developing Murine Prefrontal Cortex
Abnormal development of the prefrontal cortex (PFC) is associated with a number of neuropsychiatric disorders that have an onset in childhood or adolescence. Although the basic laminar structure of the PFC is established in utero, extensive remodeling continues into adolescence. To map the overall p...
ORGANISM(S): Mus musculus 
2006-05-15 | E-GEOD-4675 | biostudies-arrayexpress
TranscriptomicsComparison of genomic DNA amplification methods
Hybridization of amplified genomic DNA against unamplified genomic DNA using three different amplification methods to assess the bias introduced by amplification alone. Keywords: genomic DNA Three different amplification methods were assessed and total genomic DNA hybridized against equal amounts of...
ORGANISM(S): Homo sapiens 
2010-05-17 | E-GEOD-8449 | biostudies-arrayexpress
TranscriptomicsMicroRNAs in adult rodent liver and response to dioxin
This SuperSeries is composed of the following subset Series: GSE8467: Micro-RNAs in Adult Rat Liver are Refractory to 19 Hours Dioxin Exposure GSE8468: Micro-RNAs levels in wildtype vs. Ahr-null adult mouse liver constitutively and in response to doxin treatment. GSE8469: Micro-RNAs in Adult Long-E...
ORGANISM(S): Mus musculus 
2007-08-14 | E-GEOD-8474 | biostudies-arrayexpress
TranscriptomicsNanoString analysis of a rat liver mRNA panel following TCDD treatment
Profiling of mRNA abundances with high-throughput platforms such as microarrays and RNA-Seq has become an important tool in both basic and biomedical research. However these platforms remain prone to systematic errors, and have challenges in clinical and industrial application. As a result it is sta...
ORGANISM(S): Rattus norvegicus 
2013-12-31 | E-GEOD-43251 | biostudies-arrayexpress
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