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TranscriptomicsEngagement of the aryl hydrocarbon receptor in M. tuberculosis-infected macrophages has pleiotropic effects on innate immune signaling
Understanding the mechanisms of host macrophage responses to M. tuberculosis (M.tb.) is essential for uncovering potential avenues of intervention to boost host resistance to infection. Macrophage transcriptome profiling revealed M.tb. infection strongly induced expression of several enzymes control...
ORGANISM(S): Homo sapiens 
2015-07-14 | E-GEOD-70200 | biostudies-arrayexpress
GenomicsGenome-wide maps of H3K4me1 in Mycobacterium tuberculosis H37Rv-infected macrophages
Host macrophage transcriptional responses to intracellular pathogens remain poorly characterized. We screened transcriptional enhancers engaged in response to M. tuberculosis (Mtb) infection by ChIPseq analysis of histone H3 lysine 4 monomethylation (H3K4me1). De novo monomethylation during infectio...
ORGANISM(S): Homo sapiens 
2015-10-15 | E-MTAB-3192 | biostudies-arrayexpress
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