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TranscriptomicsSingle cell sequencing of iPSC-dopamine neurons reconstructs disease progression and identifies HDAC4 as a regulator of Parkinson cell phenotypes
Induced pluripotent stem cell (iPSC)-derived dopamine neurons provide an opportunity to model Parkinson’s disease (PD) but neuronal cultures are confounded by cellular heterogeneity. By applying high-resolution single cell transcriptomic analyses to Parkinson’s iPSC-derived dopamine neurons carrying...
ORGANISM(S): Homo sapiens 
2018-10-17 | E-MTAB-7303 | biostudies-arrayexpress
TranscriptomicsSNP data from induced Pluripotent Stem cells from Parkinson's Disease patients harbouring G2019S mutations in the LRRK2 gene
We have generated human induced Pluripotent Stem cells (hiPSc) using Retroviral virus-mediated delivery of reprogramming factors. hiPSc lines have been screened using SNP array to assess chromosomal stability (alongside the fibroblast lines from which they derived), and validation of the pluripotenc...
ORGANISM(S): Homo sapiens 
2016-02-09 | E-GEOD-77662 | biostudies-arrayexpress
UnknownAn immunohistochemical atlas of necroptotic pathway expression
Not available
S-SCDT-10_1038-S44321-024-00074-6 | biostudies-other
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