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TranscriptomicsEffects of bromodomain inhibitors on CD4 T+ cells under Th17-promoting conditions
The human dataset includes the gene expression profile of CD4+ T cells isolated from blood of healthy controls and plated on TCP in RPMI-1640 containing 10% FCS, Penicillin-Streptomycin (50,000 units-50 mg) and L-glutamine (2 mM). Cells were stimulated for 4 days with 20 ng/ml of IL-1beta, 100 IU/ml...
ORGANISM(S): Homo sapiens 
2015-07-23 | E-GEOD-71231 | biostudies-arrayexpress
TranscriptomicsContext-specific regulation of monocyte surface IL7R expression and soluble receptor secretion by a common autoimmune risk allele
IL-7 is a key factor in T-cell immunity and IL7R polymorphisms are implicated in susceptibility to autoimmune conditions. IL7R mRNA is induced in stimulated monocytes in a genetically determined manner. The aim this experiment was i) to characterise changes in gene expression with LPS, and ii) post-...
ORGANISM(S): Homo sapiens 
2019-08-17 | E-MTAB-8225 | biostudies-arrayexpress
GenomicsAS
WTCCC2 project samples from Ankylosing spondylitis Cohort
EGAD00010000150 | EGA
GenomicsGenomewide association studies in ankylosing spondylitis
The aim of this study was to identify genes associated with ankylosing spondylitis susceptibility in British and Australian individuals of European descent.
EGAS00000000104 | EGA
UnknownCorrelation of C-reactive protein haplotypes with serum C-reactive protein level and response to anti-tumor necrosis factor therapy in UK rheumatoid arthritis patients: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort.
Not available
S-EPMC3580526 | biostudies-literature
UnknownNon-trough adalimumab and certolizumab drug levels associated with a therapeutic EULAR response in adherent patients with rheumatoid arthritis.
Not available
S-EPMC10234202 | biostudies-literature
UnknownAssociation of a complement receptor 1 gene variant with baseline erythrocyte sedimentation rate levels in patients starting anti-TNF therapy in a UK rheumatoid arthritis cohort: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort.
Not available
S-EPMC3965567 | biostudies-literature
UnknownImpact of psychological factors on subjective disease activity assessments in patients with severe rheumatoid arthritis.
Not available
S-EPMC4153952 | biostudies-literature
UnknownSocioeconomic deprivation is associated with reduced response and lower treatment persistence with TNF inhibitors in rheumatoid arthritis.
Not available
S-EPMC10907806 | biostudies-literature
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