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TranscriptomicsGene expression of murine B cells activated via TLR4 or TLR4 + CD40: Group1 naM-CM-/ve B cells, Group2 LPS activated B cells 24h, Group3 LPS + anti-CD40 activated B cells 24h, Group4 LPS activated B cells 72h, and Group5 LPS + anti-CD40 activated B cells 72h.
Murine B cells can be activated via the surface receptors TLR4 and CD40. For a global assessment of differences in gene expression between these two different modes of B cell activation a genome wide transcriptome analysis was performed. In order to dissect different gene expression profiles of B ce...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-35998 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse NeuroD1 knockout pineal glands vs 129 wild types at P0
This study determines pineal gland gene expression levels in the NeuroD1 knockout mouse at postnatal day zero. Comparison was performed against pineal gland gene expression levels in 129 wildtype mice also disected at P0. Experiment Overall Design: Wildype 129 mice served as the reference in compari...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-6030 | biostudies-arrayexpress
TranscriptomicsConjunctival miRNA expression data in scarring and inflammatory trachoma
Ocular infection with Chlamydia trachomatis (trachoma) is the leading cause of blindness that results from infection. Chronic inflammation is believed to drive the scarring process and the progressive blinding disease, however the mechanisms by which this occurs are not completely understood. We hyp...
ORGANISM(S): Homo sapiens 
2013-06-11 | E-GEOD-37717 | biostudies-arrayexpress
TranscriptomicsGene expression profile in mouse tumor RIF-1 cell line after knockdown of Bre1a (Rnf20) or Bre1b (Rnf40).
Mammalian Bre1 complexes (BRE1A/B (RNF20/40) in humans and Bre1a/b (Rnf20/40) in mice) function similarly to their yeast homolog Bre1 as ubiquitin ligases in monoubiquitination of histone H2B. This ubiquitination facilitates methylation of histone H3 at K4 and K79, and accounts for the roles of Bre1...
ORGANISM(S): Mus musculus 
2013-01-09 | E-GEOD-34977 | biostudies-arrayexpress
UnknownRecruitment of the ParG segregation protein to different affinity DNA sites.
Not available
S-EPMC2698407 | biostudies-literature
UnknownGenome dynamics explain the evolution of flowering time CCT domain gene families in the Poaceae.
Not available
S-EPMC3454399 | biostudies-literature
TranscriptomicsExpression data from WT, MPK6 Overexpression, and mpk6 T-DNA knockout Arabidopsis root and shoot under hypoxic and mock conditions
MPK6 shows transient increase in activity under hypoxia with maximal activity at 2 hrs. To study the role of MPK6 in hypoxia in Arabidopsis, 10 do seedlings of WT, mpk6 and MPK6 plants were exposed to 2 hrs hypoxia and 2hr air (mock). Because there are no major phenotypic differences between the ge...
ORGANISM(S): Arabidopsis thaliana 
2011-12-03 | E-GEOD-31158 | biostudies-arrayexpress
UnknownDeciphering the sexual diploid members of the Boechera suffrutescens complex (Brassicaceae, Boechereae).
Not available
S-EPMC5943444 | biostudies-literature
UnknownAPOE ε4 genotype predicts memory for everyday activities.
Not available
S-EPMC4537694 | biostudies-literature
UnknownInduction of cullin 7 by DNA damage attenuates p53 function.
Not available
S-EPMC2040908 | biostudies-literature
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