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GenomicsTargeting the treponemal microbiome of digital dermatitis infections by deep coverage pyrosequencing
We examined 36 biopsies taken from digital dermatitis lesions of Holstein cows. The target was the V3 -V4 variable region of 16S rRNA using Treponema specific primers. We identified 20 different taxa of Treponema using this approach. Phylogenetic study of the Treponema taxa found in digital dermati...
ORGANISM(S): Bos taurus 
2013-06-25 | E-GEOD-42426 | biostudies-arrayexpress
TranscriptomicsGenome wide transcriptional portrait of Actinobacillus pleuropneumoniae during invasive disease reveals new strategies for survival and persistence in the host
The transcriptional profile of the porcine lung pathogen, Actinobacillus pleuropneumoniae, was monitored during the acute phase of infection in its natural host. Bacterial expression profiles of A. pleuropneumoniae isolated from lung lesions of 25 infected pigs were compared in samples taken 6, 12, ...
ORGANISM(S): Actinobacillus pleuropneumoniae 
2012-12-01 | E-GEOD-33999 | biostudies-arrayexpress
TranscriptomicsTemporal development of necrotizing enterocolitis in the preterm pig
Necrotizing enterocolitis (NEC), a serious gastrointestinal disease that afflicts 5-10% of preterm infants, often progresses rapidly from mild food intolerance into extensive haemorrhage, inflammation and necrosis. Events leading to NEC have remained poorly defined. Similar disease characteristics a...
ORGANISM(S): Sus scrofa 
2010-05-07 | E-GEOD-13516 | biostudies-arrayexpress
TranscriptomicsAmniotic fluid and necrotizing enterocolitis in preterm pigs
Preterm neonates are susceptible to gastrointestinal (GI) disorders such as necrotizing enterocolitis (NEC). Maternal milk, and especially colostrum, protects against NEC via growth promoting, immunomodulatory and antimicrobial factors. The fetal enteral diet, amniotic fluid (AF), contains similar b...
ORGANISM(S): Sus scrofa 
2010-05-06 | E-GEOD-13515 | biostudies-arrayexpress
TranscriptomicsExpression analysis of 6 serotypes of Actinobacillus pleuropneumonia during iron deprivation
Investigation of whole genome changes in six serotypes of Actinobacillus pleuropneumoniae in control cultures compared to bacteria grown in media containg the iron chelator 2,2'-dipyridyl. A 48 chip study using total RNA recovered from four different control cultures and four different iron depleted...
ORGANISM(S): Actinobacillus pleuropneumoniae serovar 2 str. 4226 
2010-10-01 | E-GEOD-24470 | biostudies-arrayexpress
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