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TranscriptomicsTranscription profiling of human low gestational age newborns as predictors of bronchopleural pulmonary dysplasia
One third to one half of all infants born before the 28th wek of gestation develop BPD bronchopulmonary dysplasia. Our objective is to evaluate the feasibility of using expression profiling in umbilical cord tissue to discover molecular signatures for developmental staging and for risk of BPD. Expe...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8586 | biostudies-arrayexpress
GenomicsmiRNA expression in tracheal aspirates [ICS-BPD vs. ICS-BPD-PH]
miRNA expression in tracheal aspirates [ICS-BPD vs. ICS-BPD-PH]
PRJNA1001305 | ENA
TranscriptomicsEffect of Nrf2 deletion in postnatal lung development and BPD phenotype in newborn mice
Background: Nrf2 is an essential cytoprotective transcription factor. However, association of Nrf2 in organ development and neonatal disease is rarely examined. Hyperoxia exposure to newborn rodents generates pulmonary phenotypes which resemble bronchopulmonary dysplasia (BPD) of prematurity. Method...
ORGANISM(S): Mus musculus 
2012-05-24 | E-GEOD-29632 | biostudies-arrayexpress
GenomicsmiRNA expression in tracheal aspirates [sBPD, BPD-PH]
miRNA expression in tracheal aspirates [sBPD, BPD-PH]
PRJNA843988 | ENA
UnknownSystemic Hydrocortisone To Prevent Bronchopulmonary Dysplasia in preterm infants (the SToP-BPD study): statistical analysis plan.
Not available
S-EPMC5845134 | biostudies-literature
GenomicsmiRNA expression in tracheal aspirates in mild/moderate and severe BPD
miRNA expression in tracheal aspirates in mild/moderate and severe BPD
PRJNA697980 | ENA
TranscriptomicsTranscriptomic Comparison of Neuronal Development Stages using Induced Pluripotent Stem Cells from Bipolar Disorder Patients
Fibroblasts from patients with Type I bipolar disorder (BPD) and their unaffected siblings were obtained from an Old Order Amish pedigree with a high incidence of BPD and reprogrammed to induced pluripotent stem cells (iPSCs). Established iPSCs were subsequently differentiated into neuroprogenitors ...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-74358 | biostudies-arrayexpress
TranscriptomicsAnti-Inflammatory Effects of Budesonide in Human Fetal Lung
Rationale. Lung inflammation in premature infants contributes to development of bronchopulmonary dysplasia (BPD), a chronic lung disease with long-term sequelae. Pilot studies administering budesonide suspended in surfactant have found reduced BPD without apparent adverse effects as occur with syste...
ORGANISM(S): Homo sapiens 
2016-06-30 | E-GEOD-83888 | biostudies-arrayexpress
TranscriptomicsmiRNA expression in tracheal aspirates [ICS-BPD vs. ICS-BPD-PH]
Tracheal aspirate (TAs) samples were collected from intubated preterm infants with hemodynamically significant intracardiac shunt (ICS), and a diagnosis of ICS-BPD/ICS-BPD-PH. 36 TA samples were analyzed. Small RNAs were extracted and the expression miRNAs was detected with PCR arrays.
ORGANISM(S): Homo sapiens 
2023-08-02 | GSE239868 | GEO
GenomicsDifferentially expressed genes in blood of BPD and Normal preterm neonates [mRNA]
Differentially expressed genes in blood of BPD and Normal preterm neonates [mRNA]
PRJNA428503 | ENA
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