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TranscriptomicsCirculating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Cell Composition
By applying RNA-ISH and RNAseq to circulating tumor cells (CTCs), the study provides definitive evidence of epithelial to mesenchymal transition (EMT) across all histological types of breast cancer, identifying mediators such as FOXC1 and TGF-β signaling, and demonstrating dynamic treatment-associat...
ORGANISM(S): Homo sapiens 
2013-02-01 | E-GEOD-41245 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of ex vivo culture of circulating breast tumor cells
Analyses of circulating tumor cells (CTC) cultured from blood of patients with cancer may allow individualized testing for susceptibility to therapeutic regimens. We established ex vivo cultures of CTCs from six patients with metastatic estrogen receptor-positive breast cancer and performed RNA-Seq...
ORGANISM(S): Homo sapiens 
2014-07-11 | E-GEOD-55807 | biostudies-arrayexpress
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