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TranscriptomicsU2AF1 mutations alter splice site recognition in hematological malignancies
Whole-exome sequencing studies have identified common mutations affecting genes encoding components of the RNA splicing machinery in hematological malignancies. Here, we sought to determine how mutations affecting the 3' splice site recognition factor U2AF1 altered its normal role in RNA splicing. W...
ORGANISM(S): Homo sapiens 
2014-09-23 | E-GEOD-58871 | biostudies-arrayexpress
UnknownComparative pharmacodynamic and pharmacokinetic study of MIDD0301 and its (S) enantiomer.
Not available
S-EPMC9246881 | biostudies-literature
UnknownExon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing.
Not available
S-EPMC6224609 | biostudies-literature
UnknownStrong CD4+ T-Cell Responses to Ancestral and Variant Spike Proteins Are Established by NVX-CoV2373 Severe Acute Respiratory Syndrome Coronavirus 2 Primary Vaccination.
Not available
S-EPMC10503953 | biostudies-literature
TranscriptomicsMNase-Seq of isolated mono-nucleosomes from strains W303 (wild-type) and htz1∆.
Chromatin transactions are typically studied in vivo, or in vitro using artificial chromatin lacking the epigenetic complexity of the natural material. Attempting to bridge the gap between these approaches, we established a system for isolating the yeast genome as a library of mono-nucleosomes harbo...
ORGANISM(S): Saccharomyces cerevisiae S288c 
2019-05-08 | E-MTAB-7926 | biostudies-arrayexpress
UnknownCoordinated missplicing of TMEM14C and ABCB7 causes ring sideroblast formation in SF3B1-mutant myelodysplastic syndrome.
Not available
S-EPMC8972092 | biostudies-literature
TranscriptomicsThe Dynamic Transcriptome of Schizosaccharomyces pombe Revealed by RNA/DNA Hybrid Mapping
We determined the strand-specific transcriptome of the fission yeast S. pombe under multiple growth conditions using a novel RNA/DNA hybridization mapping (HybMap) technique. HybMap uses an antibody against an RNA/DNA hybrid to detect RNA molecules hybridized to a high density DNA oligonucleotide ti...
ORGANISM(S): Schizosaccharomyces pombe 
2008-06-29 | E-GEOD-11619 | biostudies-arrayexpress
UnknownAssociation between Self-Reported Prior Night's Sleep and Single-Task Gait in Healthy, Young Adults: A Study Using Machine Learning.
Not available
S-EPMC9572361 | biostudies-literature
UnknownAsian inland wildfires driven by glacial-interglacial climate change.
Not available
S-EPMC7071868 | biostudies-literature
TranscriptomicsInflammasome-dependent Interferon-gamma drives pathogenesis in Streptococcus pneumoniae meningitis.
A comparison of brain gene expression profiles in wildtype mice and interferon gamma -/- mice during bacterial meningitis.
ORGANISM(S): Mus musculus 
2012-09-01 | E-MEXP-3697 | biostudies-arrayexpress
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