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ProteomicsBiophysical, proteomic, and lipidomic characterization of Streptococcus mutans extracellular membrane vesicles from wild-type, ΔsrtA, and Δsfp strains provides novel information regarding vesiculogenesis and its function
Extracellular membrane vesicles (EMVs) are produced by many Gram-positive organisms, but information regarding vesiculogenesis is largely unknown. In this study, we isolated and characterized EMVs derived from the oral pathogen Streptococcus mutans and two deletion mutants, ΔsrtA and Δsfp. ΔsrtA E...
ORGANISM(S): Streptococcus mutans serotype C 
2020-11-17 | PXD019825 | Pride
Vesicles Lipidome Proteome Streptococcus mutans Membrane 
UnknownRisk factors for GI adverse events in a phase III randomized trial of bevacizumab in first-line therapy of advanced ovarian cancer: A Gynecologic Oncology Group Study.
Not available
S-EPMC3986384 | biostudies-literature
UnknownWhen Paying Attention Pays Back: Missense Mutation c.1006G>A p. (Val336Ile) in PRKAG2 Gene Causing Left Ventricular Hypertrophy and Conduction Abnormalities in a Caucasian Patient: Case Report and Literature Review.
Not available
S-EPMC11395525 | biostudies-literature
UnknownChest compressions for pediatric organized rhythms: A hemodynamic and outcomes analysis.
Not available
S-EPMC10843614 | biostudies-literature
TranscriptomicsIdentification of candidate genes regulated by E4bp4 in murine bone marrow
E4bp4 is essential for the development of natural killer (NK) cells. We sought to identify downstream targets of E4bp4 by comparing mRNA expression in wild type vs. E4bp4 knockout Lineage-depleted bone marrow, which is enriched for haematopoietic progenitor cells. We then went on to validate these t...
ORGANISM(S): Mus musculus 
2014-03-21 | E-GEOD-55014 | biostudies-arrayexpress
ProteomicsLKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer
LKB1 is among the most frequently altered tumor suppressors in lung adenocarcinoma. Inactivation of Lkb1 accelerates the growth and progression of oncogenic KRAS-driven lung tumors in mouse models. However, the molecular mechanisms by which LKB1 constrains lung tumorigenesis and whether the aggressi...
ORGANISM(S): Mus musculus (Mouse) 
2021-12-23 | PXD026738 | Pride
Lung adenocarcinoma Mouse model Lkb1 Tumor suppressor 
TranscriptomicsTranscription profiling of human papillary serous ovarian adenocarcinomas and HUVEC and OVCA429 cells lines treated with recombinant MAGP2 - SuperSeries
This SuperSeries is composed of the following subset Series:; GSE18373: Expression data of HUVEC and OVCA429 with recombinant MAGP2; GSE18520: Whole-genome oligonucleotide expression analysis of papillary serous ovarian adenocarcinomas Experiment Overall Design: Refer to individual Series
ORGANISM(S): Homo sapiens 
2009-10-23 | E-GEOD-18521 | biostudies-arrayexpress
UnknownSpecific NEMO mutations impair CD40-mediated c-Rel activation and B cell terminal differentiation.
Not available
S-EPMC529497 | biostudies-literature
TranscriptomicsGene expression profiling of individual human oocytes and embryos
Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to other mammals. Data from assisted reproduction programmes provides additional evidence that this is largely mediated at the level of embryonic ...
ORGANISM(S): Homo sapiens 
2013-12-13 | E-MEXP-3870 | biostudies-arrayexpress
UnknownLKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer.
Not available
S-EPMC8885825 | biostudies-literature
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