Sort   by:  
 Page size 
UnknownThe spliceosomal snRNP core complex of Trypanosoma brucei: cloning and functional analysis reveals seven Sm protein constituents.
Each of the trypanosome small nuclear ribonucleoproteins (snRNPs) U2, U4/U6, and U5, as well as the spliced leader (SL) RNP, contains a core of common proteins, which we have previously identified. This core is unusual because it is not recognized by anti-Sm Abs and it associates with an Sm-related ...
S-EPMC16805 | biostudies-literature
UnknownInteractions within the yeast Sm core complex: from proteins to amino acids.
Sm core proteins play an essential role in the formation of small nuclear ribonucleoprotein particles (snRNPs) by binding to small nuclear RNAs and participating in a network of protein interactions. The two-hybrid system was used to identify SmE interacting proteins and to test for interactions bet...
S-EPMC121425 | biostudies-literature
UnknownMolecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization.
Polo-like kinase (Plk1) is crucial for cell cycle progression through mitosis. Here we present the molecular and structural mechanisms that regulate the substrate recognition of Plk1 and influence its centrosomal localization and activity. Our work shows that Plk1 localization is controlled not only...
S-EPMC1805623 | biostudies-literature
Sort   by:  
 Page size