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The p53 protein is a pivotal tumor suppressor that is frequently mutated in many human cancers, although precisely how p53 prevents tumors is still unclear. To add to its complexity several isoforms of human p53 have now been reported. The Δ133p53α isoform is generated from an alternative transcri...
ORGANISM(S): Mus musculus 
Y-box binding factor 1 (YB1) has been associated with prognosis in many tumor types. Reduction of YB-1 inhibits tumor cell growth in vitro and in vivo Total RNA was isolated from A549, MCF7 and HCT116 tumor cell lines following 48hr treatment with 5nM Yb1 siRNA
ORGANISM(S): Homo sapiens 
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