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ProteomicsDiscovery of small molecule branched-chain ketoacid dehydrogenase kinase 23 (BDK) inhibitors with opposing effects on BDK protein levels
Branched chain ketoacid dehydrogenase kinase (BDK) was immunoprecipitated from hearts of mice that had been treated with BDK inhibitors or vehicle.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-02-21 | MSV000091341 | MassIVE
UnknownReactive nitrogen species inhibit branched chain alpha-ketoacid dehydrogenase complex and impact muscle cell metabolism.
Not available
S-EPMC10656228 | biostudies-literature
UnknownSmall molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.
Not available
S-EPMC10412597 | biostudies-literature
UnknownStructural studies identify angiotensin II receptor blocker-like compounds as branched-chain ketoacid dehydrogenase kinase inhibitors.
Not available
S-EPMC9976451 | biostudies-literature
ProteomicsIntegrated amino acid profiling and 4D-DIA proteomics reveal protein quality divergence and metabolic adaptation in Cordyceps species
To explore the differences in protein quality among classic medicinal entomopatho-genic fungi and to evaluate their metabolic adaptability, we analyzed the amino acid composition and proteomic characteristics of Cordyceps sinensis (CS), Cordyceps militaris (CM) and Cordyceps cicadae (CC). Quantitati...
ORGANISM(S): Ophiocordyceps Sinensis Cordyceps Militaris Cordyceps Cicadae 
PXD063259 |
UnknownDevelopmental Defects of Caenorhabditis elegans Lacking Branched-chain α-Ketoacid Dehydrogenase Are Mainly Caused by Monomethyl Branched-chain Fatty Acid Deficiency.
Not available
S-EPMC4742758 | biostudies-literature
ProteomicsUnusual composition of the mitochondrial pyruvate dehydrogenase complex from the widespread marine protist group diplonemids
In eukaryotes, pyruvate, a key metabolite produced by glycolysis, is converted by a mitochondrial pyruvate dehydrogenase complex (PDH) to acetyl-coenzyme A, which is fed into the tricarboxylic acid cycle. Two additional enzyme complexes catalyze similar oxidative decarboxylation reactions albeit usi...
ORGANISM(S): Diplonema papillatum 
2023-07-28 | PXD035104 | Pride
Paradiplonema papillatum 2-oxoglutarate dehydrogenase Branched-chain ketoacid dehydrogenase 
UnknownStructure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase.
Not available
S-EPMC3683707 | biostudies-literature
UnknownLoss of the Drosophila branched-chain α-ketoacid dehydrogenase complex results in neuronal dysfunction.
Not available
S-EPMC7473638 | biostudies-literature
UnknownData on the proliferation and differentiation of C2C12 myoblast treated with branched-chain ketoacid dehydrogenase kinase inhibitor.
Not available
S-EPMC7276516 | biostudies-literature
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