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GenomicsComparative analysis of TAL1 binding in TSA-treated versus non-treated Endothelial Colony Forming Cells (ECFCs)
Endothelial progenitors represent one of the most promising cell-based strategies for vascular repair of ischemic tissue damage, including limb ischemia, myocardial infarction and stroke. We have shown that the transcription factor TAL1 regulates a transcription program that drives the migration and...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-53423 | biostudies-arrayexpress
TranscriptomicsshRNA mediated knock-down of Tal1 in human Endothelial Colony Forming Cells (ECFCs)
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial linea...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44444 | biostudies-arrayexpress
GenomicsGenomic binding profile of TAL1 in human Endothelial Colony-Forming Cells
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial linea...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44442 | biostudies-arrayexpress
TranscriptomicsTAL1 knock down in human erythroid progenitors
We used microarray profiling in erythroid cells to uncover TAL1 dependent genes in a hematopoietic differentiation context. Differentiated ex vivo hematopoietic multipotential progenitors isolated from adult peripheral blood. The knockdown of TAL1 (KD) was induced in pro-erythroblasts (Days 8 and 9 ...
ORGANISM(S): Homo sapiens 
2010-12-14 | E-GEOD-20545 | biostudies-arrayexpress
TranscriptomicsshRNA profiling of mouse erythroleukemia (MEL) cells and their corresponding G9a knock downs reveals a dual role for the methyltransferase G9a in the maintenance of beta-globin gene expression
MEL clone 745 cells that are blocked at the pro-erythroblast stage serve as a model for terminal erythroid differentiation when treated with DMSO. A stable MEL cell line expressing (Dox)-dependent shRNA sequence targeting different regions of G9a mRNA was established and screened as previously desc...
ORGANISM(S): Mus musculus 
2009-11-09 | E-GEOD-15620 | biostudies-arrayexpress
ProteomicsQuickProt: a bioinformatics and visualization tool for DIA and PRM mass spectrometry-based proteomics datasets
Mass spectrometry (MS)-based proteomics focuses on identifying and quantifying peptides and proteins in biological samples. Although upstream processing of MS-derived data, including deconvolution, alignment, and peptide-protein prediction, has been achieved through various platforms, the downstream...
ORGANISM(S): Homo Sapiens 
PXD060333 | panorama
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