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TranscriptomicsGene expression profiles of livers from mice fed high-fat diet and high fructose-glucose solution for 8 weeks
The lack of a preclinical model of nonalcoholic steatohepatitis (NASH) and hepatocellular cancer (HCC) that recapitulates human disease is a major barrier to therapeutic development. We report a high fat-high sugar diet-induced NASH and HCC in a stable isogenic 129S1/SvImJ crossed with C57Bl/6J mice...
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-67678 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of livers and liver tumors from mice fed high-fat diet and high fructose-glucose solution for 52 weeks
The lack of a preclinical model of nonalcoholic steatohepatitis (NASH) and hepatocellular cancer (HCC) that recapitulates human disease is a major barrier to therapeutic development. We report a high fat-high sugar diet-induced NASH and HCC in a stable isogenic 129S1/SvImJ crossed with C57Bl/6J mice...
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-67679 | biostudies-arrayexpress
TranscriptomicsA preclinical mouse model of nonalcoholic steatohepatitis and hepatocellular cancer that mimics human disease
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-67680 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in Roseburia inulinivorans grown on inulin and starch
Roseburia inulinivorans is a recently identified motile representative of the Firmicutes that contributes to butyrate formation from a variety of dietary polysaccharide substrates in the human large intestine. Microarray analysis was used here to investigate substrate-driven gene expression changes ...
ORGANISM(S): Roseburia inulinivorans DSM 16841 
2010-07-24 | E-GEOD-22245 | biostudies-arrayexpress
UnknownCrohn's disease in endoscopic remission, obesity, and cases of high genetic risk demonstrates overlapping shifts in the colonic mucosal-luminal interface microbiome.
Not available
S-EPMC9377146 | biostudies-literature
UnknownSafety of perioperative treatment with biologics in patients with inflammatory bowel disease undergoing bowel surgery: Experience from a large urban center.
Not available
S-EPMC10796016 | biostudies-literature
UnknownA pilot study on the efficacy of GPT-4 in providing orthopedic treatment recommendations from MRI reports.
Not available
S-EPMC10656559 | biostudies-literature
TranscriptomicsLiver mRNA microarray study for mice treated with various diets
The goal of this study was to investigate the effects of vairous diets on the expression of genes involved in intermediary metabolism in liver. Adult wild type male mice (3 for each group) were fed with the corresponding diet for two weeks, and then liver samples were collected. Total RNA was isolat...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-51885 | biostudies-arrayexpress
UnknownA Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition.
Not available
S-EPMC5037008 | biostudies-literature
UnknownGenome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
Not available
S-EPMC5540332 | biostudies-literature
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