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MetabolomicsNext-generation biomonitoring of the early-life chemical exposome in neonatal and infant development

Exposure to synthetic and natural chemicals is a major environmental risk factor in the etiology of many chronic diseases. Investigating complex co-exposures is necessary for a holistic assessment in exposome-wide association studies. In this work, a sensitive liquid chromatography-tandem mass sp...

2023-10-26 | MTBLS2442 | MetaboLights
TranscriptomicsTranscriptional Profiling of isolated mouse heart cardiomyocytes and non-cardiomyocytes
Profiling of transcripts specific for cardiomyocytes and non-cardiomyocytes in the mouse heart. Cells were isolated according to: MiRNA-1/133a Clusters Regulate Adrenergic Control of Cardiac Repolarization. Besser J, Malan D, Wystub K, Bachmann A, Wietelmann A, Sasse P, Fleischmann BK, Braun T*, Bo...
ORGANISM(S): Mus musculus 
2025-07-23 | E-MTAB-15342 | biostudies-arrayexpress
UnknownTL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation.
Not available
S-EPMC2605110 | biostudies-literature
ProteomicsAlpha-synuclein fibrils induce budding of mitochondrial-derived vesicles
α-synuclein (α-syn) aggregation is a hallmark of synucleinopathies, a class of neurodegenerative disorders such as Parkinson’s disease (PD). Several lines of evidence indicate the involvement of mitochondria in the disease pathology. Despite extensive study, the link between α-syn aggregation and me...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD078690 | Pride
OtherAdvanced identification of proteins in uncharacterized proteomes by pulsed in vivo SILAC
TRANCHE KEY: EfXsK8WKQKnCiGubVrXxCmmygO9Wbb8TYBBFZgdSBwla6M3AjwhqeHpWgNp8DijuGCbKH49+jBc625dSmgLPaNuv0JgAAAAAAAAB0w== Newt Tail Raw Data 12. A pulsed SILAC-based mass spectrometry method was used , which is based on the detection of paired peptides after 13C6-lysine incorporation into proteins in vi...
ORGANISM(S): Stropicalis Ncbi, Xlaevis Ncbi, Caudata 
GPM32300000779 | GPMDB
TranscriptomicsTranscriptome sequencing and comparative transcriptome analysis of the scleroglucan producer Sclerotium rolfsii
Two S. rolfsii transcriptomes obtained from scleroglucan-producing and scleroglucan-nonproducing conditions were pooled and sequenced using the 454 pyrosequencing technique yielding ~350,000 reads. These could be assembled into 21,937 contigs and 171,833 singletons, for which 6,951 had significant m...
ORGANISM(S): Athelia rolfsii 
2010-05-15 | E-GEOD-21040 | biostudies-arrayexpress
MetabolomicsCharacterizing COPD phenotypes with a targeted signaling lipids metabolomics approach

A targeted metabolomics approach reveals distinct metabolic patterns associated with different GOLD stages, KNGF profiles and SYS subtypes in COPD patients, highlighting unique mechanisms and pathways underlying various COPD classification systems.

2025-07-21 | MTBLS11748 | MetaboLights
Transcriptomicsmyocardial infarction in Reg3beta knock-out mice
Affymetrix microarray analysis of molecular changes after myocardial infarction. Samples of heart tissue were analyzed after myocardial infarction from WT and reg3beta knock-out mice. Samples from scar tissue and samples adjacent to the scar were analyzed. In the experiment we primarily compared inf...
ORGANISM(S): Mus musculus 
2015-06-29 | E-MTAB-2561 | biostudies-arrayexpress
TranscriptomicsGene Array Analyzer (GAA): Alternative usage of gene arrays to study alternative splicing events (MoGene array)
The latest version of microarrays released by Affymetrix, the GeneChip Gene 1.0 ST Arrays (gene arrays), are designed in a similar fashion as exon arrays, which enables to identify differentially expressed exons, rather than only the expression level of whole transcripts. Here, we propose an extensi...
ORGANISM(S): Mus musculus 
2011-11-28 | E-GEOD-30429 | biostudies-arrayexpress
TranscriptomicsGene Array Analyzer (GAA): Alternative usage of gene arrays to study alternative splicing events (MoEx array)
The latest version of microarrays released by Affymetrix, the GeneChip Gene 1.0 ST Arrays (gene arrays), are designed in a similar fashion as exon arrays, which enables to identify differentially expressed exons, rather than only the expression level of whole transcripts. Here, we propose an extensi...
ORGANISM(S): Mus musculus 
2011-11-28 | E-GEOD-32998 | biostudies-arrayexpress
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