Sort   by:  
 Page size 
GenomicsBRD7 is a candidate tumour suppressor gene required for p53 function
Oncogene-induced senescence (OIS) is a p53-dependent defence mechanism against uncontrolled proliferation. Consequently, many human tumours harbour p53 mutations while others show a dysfunctional p53 pathway, frequently by unknown mechanisms. We identified BRD7, a bromodomain-containing protein whos...
ORGANISM(S): Homo sapiens 
2010-03-14 | E-GEOD-20076 | biostudies-arrayexpress
TranscriptomicsHuman BJ fibroblasts containing control vs. BRD7 shRNA
Transcriptional profiling of human BJ fibroblasts comparing control FF shRNA expressing cells vs. BRD7 shRNA expressing cells under two conditions, either untreated or treated with 8uM nutln-3a for 8 hours. This experiment was done using two independent shRNAs targeting BRD7. Nutlin-3a was used to s...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-22607 | biostudies-arrayexpress
TranscriptomicsBrd7, a novel PBAF-specific SWI/SNF subunit, is required for gene activation and repression in embryonic stem cells
The composition of chromatin remodeling complexes dictates how these enzymes control transcriptional programs and cellular identity. Here, we investigate the composition of SWI/SNF complexes in embryonic stem cells (ESCs). In contrast to differentiated cells, ESCs have a biased incorporation of cert...
ORGANISM(S): Mus musculus 
2010-03-04 | E-GEOD-7791 | biostudies-arrayexpress
GenomicsBRD7 overexpression cells
BRD7 overexpression cells
PRJNA275626 | ENA
Genomicsthe effect of knockout Brd7 on 4T07-TGL cells under in vitro condition
the effect of knockout Brd7 on 4T07-TGL cells under in vitro condition
PRJNA1081885 | ENA
GenomicsGenome-wide maps of Brd7 binding sites in control and BRD7 overexpressed cells.
We applied Chromatin immunoprecipation and massively parallel DNA sequencing technique, ChIP-seqencing, to identify the binding sites of Brd7 protein in human cells. ChIP-seq was applied to HEK293 cell line in control and BRD7 overexpressed cells.
ORGANISM(S): Homo sapiens 
2018-02-12 | GSE65974 | GEO
GenomicsThe effect of knockout Brd7 on 4T07-TGL cells under in vitro condition
The effect of knockout Brd7 on 4T07-TGL cells under in vitro condition
PRJNA1090500 | ENA
UnknownBRD7 improves glucose homeostasis independent of IRS proteins.
Not available
S-EPMC10430774 | biostudies-literature
GenomicsThe effect of knockout Brd7 on 4T07-TGL cells under in vitro condition [RNA-seq]
The effect of knockout Brd7 on 4T07-TGL cells under in vitro condition [RNA-seq]
PRJNA1110227 | ENA
UnknownBRD7: a novel tumor suppressor gene in different cancers.
Not available
S-EPMC4846923 | biostudies-literature
Sort   by:  
 Page size