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TranscriptomicsGene Expression and Comparative Genomic Hybridization of Ductal Carcinoma In Situ of the Breast
Background The dramatic increase in incidence of ductal carcinoma in situ (DCIS) associated with mammographic screening for breast cancer has given emphasis to the challenges of managing this important clinical entity. Unlike invasive breast cancer, there is no established histopathologic grading sy...
ORGANISM(S): Homo sapiens 
2008-11-24 | E-GEOD-7882 | biostudies-arrayexpress
MetabolomicsOrganotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptations
BACKGROUND: Ductal carcinoma in situ (DCIS) is the earliest stage of breast cancer. During DCIS, tumor cells remain inside the mammary duct, growing under a microenvironment characterized by hypoxia, nutrient starvation, and waste product accumulation; this harsh microenvironment promotes genomic in...
2019-02-08 | MTBLS669 | MetaboLights
TranscriptomicsDifferentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer
This SuperSeries is composed of the following subset Series: GSE41194: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer (Group 1) GSE41196: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive...
ORGANISM(S): Homo sapiens 
2012-09-29 | E-GEOD-41228 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human ductal carcinoma in situ (DCIS) and invasive component (IDC) from 9 breast cancers to identify novel molecular markers characterizing the transition from DCIS to IDC.
This is a matched-pair analysis of ductal carcinoma in situ (DCIS) and invasive component (IDC) of nine breast ductal carcinoma to identify novel molecular markers characterizing the transition from DCIS to IDC for a better understanding of its molecular biology.
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-3893 | biostudies-arrayexpress
TranscriptomicsExpression profiling of murine DCIS and invasive ductal breast carcinoma
Murine healthy tissue samples, DCIS and invasive mammary tumors were analyzed in order to identify marker genes which show enhanced expresssion in DCIS and invasive ductal carcinomas. Using this approach, we were able to identify a set of genes which might allow a better detection of DCIS and invasi...
ORGANISM(S): Mus musculus 
2011-04-11 | E-GEOD-21444 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lobular and ductal invasive carcinomas vs normal breast tissue from the same patient to identify gene expression profiles of ductal and lobular carcinomas in relation to normal ductal and lobular cells
The aim of our study was to identify gene expression profiles of ductal and lobular carcinomas in relation to normal ductal and lobular cells. We examined ten mastectomy specimens from postmenopausal breast cancer patients. Ductal and lobular tumor and normal cells were microdissected from cryosecti...
ORGANISM(S): Homo sapiens 
2007-11-01 | E-GEOD-5764 | biostudies-arrayexpress
TranscriptomicsExpression profiling of human DCIS and invasive ductal breast carcinoma
Human healthy tissue samples, DCIS and invasive mammary tumors were analyzed in order to identify marker genes which show enhanced expresssion in DCIS and invasive ductal carcinomas. Using this approach, we were able to identify a set of genes which might allow a better detection of DCIS and invasiv...
ORGANISM(S): Homo sapiens 
2011-04-11 | E-GEOD-21422 | biostudies-arrayexpress
TranscriptomicsSpatial transcriptomic analyses of triple negative and luminal A breast ductal carcinoma in situ
This experiment includes GeoMx spatial transcriptomic analyses of FFPE tissue from breast ductal carcinoma in situ lesions from 16 patients. All lesions were subject to ER, PR, HER2 and Ki67 immunohistochemistry and assigned a molecular subtype. The main aim was to compare DCIS of the two subtypes T...
ORGANISM(S): Homo sapiens 
2026-06-26 | E-MTAB-16918 | biostudies-arrayexpress
TranscriptomicsDuctal Carcinoma Progression
To obtain insight into the molecular basis of ductal carcinoma in situ (DCIS) and its progression by infiltrating surrounding tissue, we have performed cellular-based gene expression analysis of pure DCIS and DCIS with co-existing invasive ductal carcinoma (IDC) and compared the histological and mol...
ORGANISM(S): Homo sapiens 
2008-04-04 | E-GEOD-11042 | biostudies-arrayexpress
ProteomicsBreast cancer proteome landscape
Proteome characterization of 45 breast tumors using HiRIEF nanoLC-MS/MS.
ORGANISM(S): Homo Sapiens (human) 
2019-02-04 | PXD008841 | JPOST Repository
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