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TranscriptomicsHairpin Capture of DNA End Structures reveals chromosomal DNA end structure with single nucleotide resolution
The structure of broken DNA ends is a critical determinant of the pathway used for DNA double strand break (DSB) repair. Here, we develop an approach, hairpin capture of DNA end structures (HCoDES), which elucidates chromosomal DNA end structures at single nucleotide resolution. HCoDES defines str...
ORGANISM(S): Mus musculus 
2014-12-03 | E-GEOD-62534 | biostudies-arrayexpress
TranscriptomicsHematopoietic Stem Cell Differentiation Regulated by a Single Ubiquitin Ligase: Substrate Complex
Hematopoietic stem cell (HSC) differentiation is regulated by cell-intrinsic and extrinsic cues. In addition to transcriptional regulation, post-translational regulation may also control HSC differentiation. To test this hypothesis, we visualized ubiquitin-regulated protein stability of a single tra...
ORGANISM(S): Mus musculus 
2010-03-07 | E-GEOD-19502 | biostudies-arrayexpress
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