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ProteomicsMultiple myeloma derived extracellular vesicle uptake by monocyte cells stimulates secretion of IL-6 and MMP9 and promotes cancer cell migration and proliferation.
Multiple Myeloma (MM) is an incurable haematological malignancy caused by uncontrolled growth of plasma cells. MM pathogenesis is largely attributed to crosstalk between plasma cells and the bone marrow microenvironment (BMM), where extracellular vesicles (EVs) are reported to play a role. Improved ...
ORGANISM(S): Homo sapiens (Human) 
2024-08-26 | PXD047285 | Pride
Multiple myeloma Extracellular vesicle Cancer cell migration. 
ProteomicsIdentification of bone marrow and peripheral blood plasma extracellular vesicle protein biomarker signatures for multiple myeloma diagnosis and staging
Multiple myeloma (MM) is a hematological malignancy characterised by the clonal proliferation of abnormal plasma cells within the bone marrow (BM). Despite advances in treatment that have improved survival, the disease remains incurable. MM diagnosis requires invasive bone marrow biopsy to quantify ...
ORGANISM(S): Homo sapiens (Human) 
2026-08-24 | PXD069556 | Pride
Machine learning Cancer Multiple myeloma Extracellular vesicles Biomarker signature Proteomic 
ProteomicsIsolation and Characterisation of EVs from Feline Plasma: A Comparative Analysis with Human Plasma Derived EVs
Extracellular vesicles (EVs) are nanoparticles found in all biological fluids, capable of transporting biological material around the body. Extensive research into the physiological role of EVs has led to the development of the Minimal Information for Studies of Extracellular Vesicles (MISEV) framew...
ORGANISM(S): Homo sapiens (Human) 
2022-07-13 | PXD034369 | Pride
Human Extracellular vesicles Cat Bruker timstof pro 
UnknownPlasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer: the STAMPEDE Phase 3 Randomized Clinical Trial.
Not available
S-EPMC11869088 | biostudies-literature
UnknownMetformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol.
Not available
S-EPMC12303861 | biostudies-literature
UnknownMachine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score.
Not available
S-EPMC8344569 | biostudies-literature
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