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TranscriptomicsChanges in gene expression induced by CDK9 inhibition alone and in combination with fludarabine
Using a transcriptomics approach we explored the mechanism(s) of synergy observed between CDKI-73 and fludarabine in primary CLL cells. The cytotoxic effects of CDKI-73 were associated with transcriptional inhibition of cdk9 target genes including MCL1 and XIAP. In contrast, fludarabine induced the ...
ORGANISM(S): Homo sapiens 
2013-06-25 | E-GEOD-48258 | biostudies-arrayexpress
UnknownConfirmation of putative HIV-1 group P in Cameroon.
Not available
S-EPMC3020498 | biostudies-literature
UnknownCDH3-AS1 antisense RNA enhances P-cadherin translation and acts as a tumor suppressor in melanoma.
Not available
S-EPMC11703152 | biostudies-literature
UnknownThe nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus.
Not available
S-EPMC8789054 | biostudies-literature
UnknownRole of unusual P loop ejection and autophosphorylation in HipA-mediated persistence and multidrug tolerance.
Not available
S-EPMC4831868 | biostudies-literature
UnknownStructures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators.
Not available
S-EPMC3074128 | biostudies-literature
UnknownOutcomes of Patients With Acute Low Back Pain Stratified by the STarT Back Screening Tool: Secondary Analysis of a Randomized Trial.
Not available
S-EPMC5804017 | biostudies-literature
UnknownA novel fibrinogen mutation: FGA g. 3057 C > T (p. Arg104 > Cys) impairs fibrinogen secretion.
Not available
S-EPMC5741905 | biostudies-literature
Unknown2,3-cis-2R,3R-(-)-epiafzelechin-3-O-p-coumarate, a novel flavan-3-ol isolated from Fallopia convolvulus seed, is an estrogen receptor agonist in human cell lines.
Not available
S-EPMC3695784 | biostudies-literature
ProteomicsFERM domain protein 3 Kidney Biopsy
We examined the transcriptional profile of human kidney biopsies, aiming to provide insight into the mechanisms of progressive CKD. This approach led to the identification of FERM domain protein 3, (FRMD3) as a molecular driver of disease. Transcriptome profiling was performed in human renal biopsy ...
ORGANISM(S): Homo sapiens (Human) 
2024-11-06 | PXD015297 | Pride
Kidney human ferm domain protein 3 
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