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ProteomicsStress-induced translation inhibition through displacement of scanning initiation factors
Cellular responses to environmental stress are frequently mediated by RNA-binding proteins (RBPs). Here, we examined global RBP dynamics in Saccharomyces cerevisiae in response to glucose starvation and heat shock. Each stress induced rapid remodeling of the protein:RNA interactome, without correspo...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-10-13 | PXD019141 | Pride
Translational control. Heat shock Glucose starvation Environmental stress Initiation factors Rna-binding proteins Mrna Translation 
ProteomicsIntegrative Vectors for Regulated Expression of SARS-CoV-2 Proteins Implicated in RNA Metabolism
Infection with SARS-CoV-2 is expected to result in substantial reorganization of host cell RNA metabolism. We identified 14 proteins that were predicted to interact with host RNAs and/or RNA binding proteins, based on published data for SARS-CoV and SARS-CoV-2. Here, we describe a series of affinity...
ORGANISM(S): Homo sapiens (Human) 
2020-09-25 | PXD020339 | Pride
Covid-19  fusion proteins  uv crosslinking  rna 
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