Sort   by:  
 Page size 
TranscriptomicsTargeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
Bromodomain inhibition comprises a promising therapeutic strategy in cancer, particularly for hematologic malignancies. To date, however, genomic biomarkers to direct clinical translation have been lacking. We conducted a cell-based screen of genetically-defined cancer cell lines using a prototypica...
ORGANISM(S): Homo sapiens 
2013-02-25 | E-GEOD-43392 | biostudies-arrayexpress
TranscriptomicsNeuroblastoma cell lines
Untreated neuroblastoma cell lines SMS-KCN, SMS-KCNR, Kelly, and SH-SY5Y were sequenced on an Illumina GA IIx sequencer.
ORGANISM(S): Homo sapiens 
2014-12-30 | E-MTAB-2690 | biostudies-arrayexpress
GenomicsThe Scc2NIPBL/Scc4MAU2 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions [Mnase-seq]
The Scc2/Scc4 complex binds to broad nucleosome-free regions in the promoters of highly expressed genes. The cohesin loader is recruited to these sites by the RSC chromatin remodeling complex MNase digestion of purified DNA followed by paired-end sequencing was performed in order to investigate geno...
ORGANISM(S): Saccharomyces cerevisiae 
2014-08-01 | E-GEOD-56992 | biostudies-arrayexpress
UnknownSARS-CoV-2 antibody persistence in COVID-19 convalescent plasma donors: Dependency on assay format and applicability to serosurveillance.
Not available
S-EPMC8447038 | biostudies-literature
ProteomicsMass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancer

Filip Mundt, Sandeep Rajput, Shunqiang Li, Kelly Ruggles, Arshag D. Mooradian, Philipp Mertins, Michael A. Gillette, Karsten Krug, et al., Cancer Res. 2018 May 15;78(10):2732-2746. doi: 10.1158/0008-5472.CAN-17-1990.

Activation of phosphoinositide 3-kinase (PI3K) signaling is frequently obs...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-10-19 | MSV000083050 | MassIVE
MetabolomicsComprehensive systems biology analysis of a seven-month cigarette smoke inhalation study in C57BL/6 mice
Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of smoke derived from a prototype modified risk tobacco product (pMRTP) as compare...
2015-11-19 | MTBLS143 | MetaboLights
Unknownk-mer genome-wide association study for anthracnose and BCMV resistance in a Phaseolus vulgaris Andean Diversity Panel.
Not available
S-EPMC11628888 | biostudies-literature
UnknownIdentifying Inhibitors of -1 Programmed Ribosomal Frameshifting in a Broad Spectrum of Coronaviruses.
Not available
S-EPMC8876150 | biostudies-literature
UnknownSuitability of Slower Growing Commercial Turkey Strains for Organic Husbandry in Terms of Animal Welfare and Performance.
Not available
S-EPMC7873929 | biostudies-literature
GenomicsThe effects of the global loss of DNA methylation on the functional cancer epigenome (K562 WGBS/whole-genome NOMe-seq)
We assess global chromatin accessibility following high salt wash Simultaneous genome-wide mapping of DNA methylation and nucleosome occupancy of K562 cells
ORGANISM(S): Homo sapiens 
2015-02-06 | E-GEOD-64929 | biostudies-arrayexpress
Sort   by:  
 Page size