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TranscriptomicsGene expression changes in the periventricular white matter of neonatal piglets at a defined 48h time point following a hypoxic-ischemic insult: a comparison of piglets left untreated and those treated with a remote post-conditioning stimulus applied to the hind leg immediately after the insult.
Remote ischemic postconditioning (RIPostC) is a promising therapeutic intervention whereby brief episodes of ischemia/reperfusion of one organ (limb) mitigate damage in another organ (brain) that has experienced severe hypoxia-ischemia. 16 Large White newborn female piglets were exposed to a tightl...
ORGANISM(S): Sus scrofa 
2016-09-21 | E-MTAB-5125 | biostudies-arrayexpress
TranscriptomicsTBP ChIP-chip on Jurkat cells
During mitosis, TATA-binding protein(TBP), which remains bound to DNA during mitosis, recruits PP2A and also interacts with a subunit of the condensin complex to allow efficient dephosphorylation and inactivation of condensin near these promoters to inhibit their compaction. These result suggest tha...
ORGANISM(S): Homo sapiens 
2010-04-03 | E-GEOD-12256 | biostudies-arrayexpress
TranscriptomicsGene expression studies of a human monocyte cell line identify dissimilarities between Copaxone and Probioglat
Glatiramer Acetate (GA) has provided safe and effective treatment for multiple sclerosis (MS) patients for two decades. It acts as an antigen, yet the precise mechanism of action remains to be fully elucidated, and no validated pharmacokinetic or pharmacodynamic biomarkers exist. In order to bette...
ORGANISM(S): Homo sapiens 
2015-05-22 | E-GEOD-68527 | biostudies-arrayexpress
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