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TranscriptomicsBET Bromodomains Mediate Transcriptional Pause Release in Heart Failure [NRVM Expression]
Heart failure (HF) is driven via interplay between master regulatory transcription factors and dynamic alterations in chromatin structure. While pathologic gene transactivation in this context is known to be associated with recruitment of histone acetyl-transferases and local chromatin hyperacetylat...
ORGANISM(S): Rattus norvegicus 
2013-08-06 | E-GEOD-48111 | biostudies-arrayexpress
TranscriptomicsBET Bromodomains Mediate Transcriptional Pause Release in Heart Failure [Mouse Heart Expression]
Heart failure (HF) is driven via interplay between master regulatory transcription factors and dynamic alterations in chromatin structure. While pathologic gene transactivation in this context is known to be associated with recruitment of histone acetyl-transferases and local chromatin hyperacetylat...
ORGANISM(S): Mus musculus 
2013-08-06 | E-GEOD-48110 | biostudies-arrayexpress
GenomicsBET Bromodomains Mediate Transcriptional Pause Release in Heart Failure [ChIP-Seq]
Heart failure is driven by the interplay between master regulatory transcription factors and dynamic alterations in chromatin structure. Coordinate activation of developmental, inflammatory, fibrotic and growth regulators underlies the hallmark phenotypes of pathologic cardiac hypertrophy and contra...
ORGANISM(S): Mus musculus 
2013-08-06 | E-GEOD-46668 | biostudies-arrayexpress
UnknownStructural features and inhibitors of bromodomains.
Not available
S-EPMC5325140 | biostudies-literature
GenomicsPBRM1 bromodomains associate with RNA to facilitate chromatin association (CLIP-seq)
PBRM1 bromodomains associate with RNA to facilitate chromatin association (CLIP-seq)
PRJNA915087 | ENA
GenomicsPBRM1 bromodomains associate with RNA to facilitate chromatin association (ChIP-seq)
PBRM1 bromodomains associate with RNA to facilitate chromatin association (ChIP-seq)
PRJNA915088 | ENA
UnknownProtein dynamics and structural waters in bromodomains.
Not available
S-EPMC5659604 | biostudies-literature
UnknownEngineered bromodomains to explore the acetylproteome.
Not available
S-EPMC4535431 | biostudies-literature
Unknown[1,2,4]triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains.
Not available
S-EPMC3906316 | biostudies-literature
UnknownDihydropyridine Lactam Analogs Targeting BET Bromodomains.
Not available
S-EPMC8762755 | biostudies-literature
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