Sort   by:  
 Page size 
TranscriptomicsGene expression profiling in blood of patients with chronic respiratory failure
Genes dysregulated in cystic fibrosis (CF) and primary pulmonary arterial hypertension (PAH) at a late stage of pulmonary failure are still largely unknown. Blood samples taken in the frame of the French cohort of lung transplantation COLT offers the opportunity to identify in blood specific gene si...
ORGANISM(S): Homo sapiens 
2014-12-09 | E-GEOD-38267 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in B lymphocytes from transplanted patients
The achievement of a drug-free operational tolerance for renal transplanted patients is a major goal in organ transplantation. Previous gene expression profiling in peripheral blood mononuclear cells (PBMC) identified genes associated with operational tolerance. The identification of a common patter...
ORGANISM(S): Homo sapiens 
2015-08-01 | E-GEOD-39899 | biostudies-arrayexpress
TranscriptomicsIndices of Tolerance (IOT): Cross-platform biomarkers that identify kidney transplant tolerance
Being able to identify patients in whom immunological tolerance has been established or is developing would allow an individually tailored approach to post-transplant management of kidney allograft recipients. Ex vivo immunological monitoring was performed on samples from five groups of European ren...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-14655 | biostudies-arrayexpress
TranscriptomicsIdentification of genes differentially expressed between control and SMILE siRNA transfected HeLa cells
SMILE, a molecule for which no information is available in the literature, is overexpressed in the blood of patients tolerating a kidney graft without treatment. We performed microarray analysis to determine cellular functions affected by SMILE silencing. Each condition of control and SMILE siRNA tr...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-21886 | biostudies-arrayexpress
TranscriptomicsComparison between syngeneic kidney transplant and a model of allogeneic kidney transplant tolerance induced by anti-classII regimen in the rat
The goal is to identify new molecules implicated in tolerance, to determine the implication of these molecules in immune responses to transplantation by gene expression comparison of 27,088 individual rat genes between tolerated kidney allotransplant and syngeneic kidney transplant. In this study 27...
ORGANISM(S): Rattus norvegicus 
2011-04-09 | E-GEOD-28474 | biostudies-arrayexpress
TranscriptomicsComparative Transcriptional and Phenotypic Peripheral Blood Analysis of Kidney Recipients under Cyclosporin A or Sirolimus Monotherapy
Due to its low level of nephrotoxicity and capacity to harness tolerogenic pathways, sirolimus (SRL) has been proposed as an alternative to calcineurin inhibitors in transplantation. The exact mechanisms underlying its unique immunosuppressive profile in humans, however, are still not well understoo...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-22224 | biostudies-arrayexpress
Sort   by:  
 Page size