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MetabolomicsImidazole ketone erastin induces ferroptosis and slows tumor growth in a mouse lymphoma model
Ferroptosis is a form of regulated cell death that can be induced by inhibition of the cystine-glutamate antiporter, system xc-. Among the existing system xc- inhibitors, imidazole ketone erastin (IKE) is a potent, metabolically stable inhibitor of system xc- and inducer of ferroptosis potentially s...
2019-04-17 | MTBLS774 | MetaboLights
UnknownCognitive-behavioral therapy for suicide prevention (CBT-SP): treatment model, feasibility, and acceptability.
Not available
S-EPMC2888910 | biostudies-literature
UnknownCRISPR-mediated knockout of cardinal and cinnabar eye pigmentation genes in the western tarnished plant bug.
Not available
S-EPMC8943060 | biostudies-literature
MetabolomicsEnergy-stress-mediated AMPK activation inhibits ferroptosis

Energy stress depletes ATP and induces cell death. Here we identify an unexpected inhibitory role of energy stress on ferroptosis, a form of regulated cell death induced by iron-dependent lipid peroxidation. We found that ferroptotic cell death and lipid peroxidation can be inhibited by treatment...

2023-01-31 | MTBLS1399 | MetaboLights
UnknownEmergence of SARS-CoV-2 Alpha (B.1.1.7) variant, infection rates, antibody seroconversion and seroprevalence rates in secondary school students and staff: Active prospective surveillance, December 2020 to March 2021, England.
Not available
S-EPMC8361003 | biostudies-literature
TranscriptomicsTranscription profiling of S. cerevisiae response to Oxygen, Heme and Cobalt
Yeast cell growth and treatment:; Yeast strains used were L51 (MATa, ura3-52, leu2-3, 112, his4-519, ade1-100, trp1::HisG, hap1::LEU2) and MHY100 (MATa, ura3-52, leu2-3, 112, his4-519, ade1-100, hem1-delta100). L51 was used for studies of oxygen regulation, and MHY100 was used for studies of heme r...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-25 | E-GEOD-8343 | biostudies-arrayexpress
UnknownAdjunctive sleep medications and depression outcome in the treatment of serotonin-selective reuptake inhibitor resistant depression in adolescents study.
Not available
S-EPMC3281285 | biostudies-literature
UnknownDasatinib Plus Intensive Chemotherapy in Children, Adolescents, and Young Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Results of Children's Oncology Group Trial AALL0622.
Not available
S-EPMC6067800 | biostudies-literature
UnknownSARS-CoV-2 infection, antibody positivity and seroconversion rates in staff and students following full reopening of secondary schools in England: A prospective cohort study, September-December 2020.
Not available
S-EPMC8343251 | biostudies-literature
TranscriptomicsThe effect of GW3965 and dexamethasone on gene expression of rat livers
GLUCOCORTICOIDS are steroid hormones that strongly influence intermediary carbohydrate metabolism by increasing the transcription rate of glucose-6-phosphatase (G6Pase) a key enzyme of gluconeogenesis, and suppress the immune system which makes them one of the most important therapeutic agents in th...
ORGANISM(S): Rattus norvegicus 
2012-04-01 | E-GEOD-29912 | biostudies-arrayexpress
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