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MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
TranscriptomicsNutrient-regulated transcriptional responses in the brown tide forming alga Aureococcus anophagefferens
Relatively little is known about the presence and regulation of pathways involved in nutrient acquisition in the brown tide forming alga, Aureococcus anophagefferens. In this study, Long-SAGE (Serial Analysis of Gene Expression) was used to profile the A. anophagefferens transcriptome under nutrien...
ORGANISM(S): Aureococcus anophagefferens 
2010-11-05 | E-GEOD-21465 | biostudies-arrayexpress
TranscriptomicsZbtb16 Has a Role in Brown Adipocyte Bioenergetics
Study designed to identify genes that are induced in both BAT and skeletal muscle during acute adaptive thermogenesis in mouse using gene expression microarray. Animal studies were performed under approved UCLA animal research protocols and according to guidelines established in the Guide for Care ...
ORGANISM(S): Mus musculus 
2012-08-31 | E-GEOD-40486 | biostudies-arrayexpress
MetabolomicsSoftware tool for internal standard based normalization of lipids, and effect of data-processing strategies on resulting values

BACKGROUND: Lipidomics, the comprehensive measurement of lipids within a biological system or substrate, is an emerging field with significant potential for improving clinical diagnosis and our understanding of health and disease. While lipids diverse biological roles contribute ...

2022-05-17 | MTBLS710 | MetaboLights
TranscriptomicsMapping of Three Genetic Determinants of Susceptibility to Estrogen-Induced Mammary Cancer within the Emca8 Locus on Rat Chromosome 5
We are using the ACI rat model of 17beta-estradiol induced mammary cancer to define the mechanisms through which estrogens contribute to breast cancer development; identify and functionally characterize the genetic variants that determine susceptibility; and define the hormone-gene-environment inter...
ORGANISM(S): Rattus norvegicus 
2013-02-08 | E-GEOD-39788 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast treated with rapamycin in a 7-part time series
This experiment was a 7-part time series (or, 2x7 factorial design) examining the effect of rapamycin on gene expression in Saccharomyces cerevisiae. Treated and untreated cultures were compared at 0, 20, 40, 60, 120, 240, and 360 minutes. In the paper, expression ratios (mRNA) at each time point ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-02-05 | E-TABM-639 | biostudies-arrayexpress
UnknownBeyond the Angstrom Exponent: Probing Additional Information in Spectral Curvature and Variability of In Situ Aerosol Hyperspectral (0.3-0.7 μm) Optical Properties.
Not available
S-EPMC9787633 | biostudies-literature
UnknownPerformance of Deep Learning Architectures and Transfer Learning for Detecting Glaucomatous Optic Neuropathy in Fundus Photographs.
Not available
S-EPMC6232132 | biostudies-literature
UnknownGlaucoma Detection and Structured OCT Report Generation via a Fine-tuned Multimodal Large Language Model.
Not available
S-EPMC12622204 | biostudies-literature
UnknownIndividualized Glaucoma Change Detection Using Deep Learning Auto Encoder-Based Regions of Interest.
Not available
S-EPMC8300051 | biostudies-literature
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