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Genomics[E-TABM-722] Transcription factor binding evolution in five vertebrates
Five-vertebrate ChIP-seq reveals the evolutionary dynamics of trancription factor binding. The SRF files for this experiment can be found in the European Read Archive with study accession number ERP000054. ArrayExpress Submission Date: Apr 07 2010 ArrayExpress Release Date: Apr 08 2010 Publication A...
ORGANISM(S): Gallus gallus Canis lupus familiaris Monodelphis domestica Homo sapiens Mus musculus 
2010-06-02 | GSE22078 | GEO
MetabolomicsClustering of chemical profiles of Centella asiatica cultivars, grown in greenhouses, allows grouping of metabolites with similar production trends
Centella asiatica (L.) Urban (also known as ""gotu kola"") is a perennial plant, used in traditional medicine for promoting resilience to central nervous system (CNS) disorders. C. asiatica is a tropical medicinal herb from the Apiaceae family and is native to Southeast Asian countries. The chemical...
2026-10-21 | MTBLS11735 | MetaboLights
UnknownLeishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances.
Not available
S-EPMC6534257 | biostudies-literature
GenomicsChIP-Seq of six mammals tissues: liver, muscle, testes with antibody against RNA polymerase III
Homologous vertebrate tissues express a highly conserved set of transcribed genes; paradoxically, expression of tRNAs that are required to translate mRNAs into proteins have been reported to be divergent. To resolve this paradox, we mapped the genome-wide occupancy of pol III in primary tissues iso...
ORGANISM(S): Homo sapiens 
2011-07-29 | E-MTAB-958 | biostudies-arrayexpress
TranscriptomicsmicroRNA sequencing in rat cardiac fibroblasts and fibroblast-derived exosomes
We found that cardiac fibroblasts produce and secrete exosomes. miRNA profiling and TaqMan qRT-PCR experiments identified miR-21 expression to be higher in cardiac fibroblasts compared to those of miR-21*, whereas in exosomes miR-21* expression was higher compared to miR-21. The purpose of the stud...
ORGANISM(S): Rattus norvegicus 
2015-12-19 | E-GEOD-76175 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of six mammals
Homologous vertebrate tissues express a highly conserved set of transcribed genes; paradoxically, expression of tRNAs that are required to translate mRNAs into proteins have been reported to be divergent. To resolve this paradox, we mapped the genome-wide occupancy of pol III in primary tissues iso...
ORGANISM(S): Mus musculus 
2011-07-29 | E-MTAB-424 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hyperthermophilic crenarchaeum Thermoproteus tenax to compare autotrophic growth on CO2/H2 versus heterotrophic growth on glucose using a focussed central carbohydrate metabolism DNA microarray
In order to unravel the role of regulation on transcript level in the central carbohydrate metabolism (CCM) of Thermoproteus tenax (glycolytic/gluconeogenic carbon switch), the focused DNA microarray was constructed by using ORFs supposed to be involved in the CCM pathways. Transcriptional profiling...
ORGANISM(S): Thermoproteus tenax 
2008-02-05 | E-MEXP-1376 | biostudies-arrayexpress
TranscriptomicsHigh fat diet leads to increased storage of mono-unsaturated fatty acids and tissue specific risk factors for disease
Analysis of tissues of DBA/2 mice fed a standard breeding diet (SBD) and high fat diet (HFD) revealed tissue specific roles in inflammation and disease, and altered communication between tissues. The tissues surveyed incuded adipose tissues (brown, inguinal, mesenteric, retro-peritoneal, subcutanei...
ORGANISM(S): Mus musculus 
2010-04-13 | E-GEOD-15822 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat efferent ductules treated with the anti-estrogen fulvestrant ICI 182780
The aim of this study was to analyze the effects of the antiestrogen fulvestrant (ICI 182,780) on gene expression of the rat efferent ductules. Thirty day-old rats were treated once a week for 2 months with vehicle (control group) or ICI 182,780 (AstraZeneca; 10 m g/rat, s.c.). Total RNA of the effe...
ORGANISM(S): Rattus norvegicus 
2008-06-09 | E-MEXP-1497 | biostudies-arrayexpress
TranscriptomicsLeukemogenesis by CDX2 involves KLF4 repression and deregulated PPARgamma signaling.
Aberrant expression of the homeodomain transcription factor CDX2 occurs in most cases of acute myeloid leukemia (AML) and promotes leukemogenesis, making CDX2, in principle, an attractive therapeutic target. Conversely, CDX2 acts as a tumor suppressor in colonic epithelium. The effectors mediating t...
ORGANISM(S): Mus musculus 
2012-12-21 | E-GEOD-40939 | biostudies-arrayexpress
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