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TranscriptomicsBarcoded mRNA-seq of murine brown preadipocytes (IBA) upon transcriptomic perturbation
Loss of function assays were performed in differentiating IBAs using short hairpin RNAs (shRNAs) against a set of candidate transcription factors: NFIA, DBP, HOXA4, ZFP467, SOX18, ELF3, YBX2 and PPARa. Gene expression profiles of the perturbed and non perturbed (controls including non transduced cel...
ORGANISM(S): Mus musculus 
2017-09-21 | E-MTAB-5161 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling of the Retina after Transcorneal Electrical Stimulation in Wildtype Brown Norway Rats
Purpose: To investigate the effect of transcorneal electrical stimulation (TES) on the retina of wildtype Brown Norway (BN) rats by gene expression profiling. Methods: TES was applied to BN adult wildtype rat retina in vivo for 1h (1ms biphasic pulses at 20Hz; current: 200 M-BM-5A). RNA was isolated...
ORGANISM(S): Rattus norvegicus 
2011-11-21 | E-GEOD-26174 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat colon tumors induced by DMH
344 rats were treated twice, one week apart, with subcutaneous injections of 1,2-dimethylhydrazine (150 mg/kg x 2). Thirty-two weeks after the first DMH injection, rats were sacrificed and colonic tumours (T) and normal colon mucosa (NM) harvested and stored in RNAlater. Genomic DNA was extracted f...
ORGANISM(S): Rattus norvegicus 
2010-07-20 | E-MEXP-2487 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat colonic tumors induced by 1,2-dimethylhydrazine (DMH)
Gene expression analysis of 1,2-dimethylhydrazine (DMH)-induced colon cancer in F344 rats. 9 tumours and their paired normal mucosa were hybridized on 4x44K Agilent Whole rat arrays.
ORGANISM(S): Rattus norvegicus 
2010-07-20 | E-MEXP-2471 | biostudies-arrayexpress
TranscriptomicsThe mRNA-bound proteome and its global occupancy profile on protein-coding transcripts [protein occupancy profiling]
Protein-RNA interactions are fundamental to core biological processes, such as mRNA splicing, localization, degradation and translation. We developed a photoreactive nucleotide-enhanced UV crosslinking and oligo(dT) purification approach to identify the mRNA-bound proteome using quantitative proteom...
ORGANISM(S): Homo sapiens 
2012-06-01 | E-GEOD-38355 | biostudies-arrayexpress
UnknownCry1C rice doesn't affect the ecological fitness of rice brown planthopper, Nilaparvata lugens either under RDV stress or not.
Not available
S-EPMC7532440 | biostudies-literature
TranscriptomicsPostia placenta MAD-698 gene expression in different media
Transscript profiles of Postia placenta grown on different substrates were analyszed. Array design was based on the DoE's Joint Genome Institute's gene models for P. placenta version 1. The research goal is to identtify genes essential for cellulose depolymerization. Keywords: Culture condition com...
ORGANISM(S): Postia placenta 
2010-05-14 | E-GEOD-12540 | biostudies-arrayexpress
TranscriptomicsEffects on gene expression in rat liver after administration of RXR agonists: UAB30, 4-methyl-UAB30, and Targretin
Examination of three retinoid X receptor (RXR) agonists [Targretin (TRG), UAB30, and 4-methyl-UAB30 (4-Me-UAB30)] showed that all inhibited mammary cancer in rodents and two (TRG and 4-Me-UAB30) strikingly increased serum triglyceride levels. Agents were administered in diets to female Sprague-Dawle...
ORGANISM(S): Rattus norvegicus 
2014-05-14 | E-GEOD-57638 | biostudies-arrayexpress
UnknownInhibition of glial D-serine release rescues synaptic damage after brain injury.
Not available
S-EPMC9305835 | biostudies-literature
TranscriptomicsChanges in transcript expression in circulating whole blood resulting from exposure to neurotoxic doses of D-amphetamine or Heat Stroke/Hyperthermia
These experiments were designed to detect transcript (mRNA) changes in whole circulating blood in animals exposed to D-amphetamine under neurotoxic and non-neurotoxic conditions, or subjected to elevated environmental temperatures that produced a hyperthermia very similar to heat stroke. The study ...
ORGANISM(S): Rattus norvegicus 
2015-12-08 | E-GEOD-64778 | biostudies-arrayexpress
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