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TranscriptomicsRNA messengers translated at the ER membrane
In order to identify what RNA messengers are being translated at the ER membrane, membrane-associated polysomes were separated from free polysomes by subcellular fractionation of WT and delta-egd1/delta-egd2 yeast strains and associated RNA was isolated and then identified by microarray analysis. Se...
ORGANISM(S): Saccharomyces cerevisiae 
2013-04-05 | E-GEOD-45795 | biostudies-arrayexpress
TranscriptomicsPolysomes
Translational profiles of wild type yeast strains were identified by microarray analysis by isolating polysomes using sucrose gradients to recover polysome-associated RNA and comparing polysome-associated RNA vs total RNA Set of arrays that are part of repeated experiments
ORGANISM(S): Saccharomyces cerevisiae 
2013-04-05 | E-GEOD-45797 | biostudies-arrayexpress
TranscriptomicsRNA coimmunoprecipitations
Nascent polypeptides emerging from the ribosome during biogenesis can interact with many chaperones and protein homeostasis factors. The high sensitivity of RNA identification can be used to identify substrates of specific cotranslationally acting chaperones. Protein A-tagged (TAP-tag) chaperones as...
ORGANISM(S): Saccharomyces cerevisiae 
2013-04-05 | E-GEOD-45794 | biostudies-arrayexpress
TranscriptomicsMicroarray gene profiling in glucocorticoid-induced Avascular Necrosis of the Femoral Head in a Rat Model
Wistar Kyoto Rats were administered glucocorticoid pellets and placebo pellets for 6 months. After 6 months rats were sacrificed and their femoral heads were histologically examined for the detection of avascular necrosis of the femoral head. Total RNA was extracted from femoral heads and submitted ...
ORGANISM(S): Rattus norvegicus 
2011-06-09 | E-MEXP-2751 | biostudies-arrayexpress
TranscriptomicsAbiraterone acetate and di-n-butyl phthalate (DBP) response in a human fetal testis xenograft bioassay
The goal of this study was to determine the effects of a well-characterized anti-androgen, abiraterone acetate, and a suspected human anti-androgen, di-n-butyl phthalate (DBP) on the androgenic function of human fetal testis. Human fetal testis was xenografted into the renal subcapsular space of cas...
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-49244 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human peripheral blood mononuclear cells exposed to red blood cells infected with Plasmodium falciparum
Peripheral Blood Mononuclear Cells were isolated from three individuals. Cells from these biological replicates were exposed to Red Blood Cells (male donor age 27) infected with Plasmodium falciparum, uninfected Red Blood Cells, or RPMI prior to stimulation with PAM3CSK4 (10g/mL) for 0, 4, and 12 h...
ORGANISM(S): Homo sapiens 
2020-05-15 | E-MTAB-9066 | biostudies-arrayexpress
MetabolomicsHuman Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including social communication and stereotypies. In addition to genetic risks, the gut microbiome differs between typically-developing (TD) and ASD individuals, though it remains unclear whether the microbiome contrib...
2019-07-04 | MTBLS726 | MetaboLights
TranscriptomicsMitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
BAT transcriptome from control and brown adipocyte-specific Rev-erbα/β double knockout mice housed at thermoneutrality or cold-challenged for 6 hours. Brown adipose tissue (BAT) samples were collected from control and brown adipocyte-specific Rev-erbα/β double knockout mice (Ucp1-Cre; Nr1d1/2 fl/fl)...
ORGANISM(S): Mus musculus 
2026-09-23 | E-MTAB-17580 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of kidney from rats of SHR/Ola, BN and SHR-18 strains after being provided with drinking water with 1% or 0% sodium chloride
Four male SHR/Ola, BN and SHR-18 rats were fed a normal diet and sacrificed at 9 weeks of age. Four male SHR/Ola and SHR-18 rats at 8 weeks of age were fed 1% NaCl for one week and then sacrificed. Kidneys were removed and frozen in liquid nitrogen for all 20 animals. Total RNA was isolated, labelle...
ORGANISM(S): Rattus norvegicus 
2008-04-01 | E-MIMR-1122 | biostudies-arrayexpress
TranscriptomicsmiRNA transcription profiling in Status Epilepticus Induced Epileptogenic Process
miRNA array comparing the transcription profile of control rats and rats after intra-hippocampal pilocarpine-induced Status Epilepticus (PILO-SE).
ORGANISM(S): Rattus norvegicus 
2016-04-28 | E-MTAB-4633 | biostudies-arrayexpress
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