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TranscriptomicsDevelopment and blind clinical validation of a microRNA based predictor of response to treatment with R-CHOEP in DLBCL
microRNAs er are group of short noncoding RNAs that regulate gene expression at the posttranslational level. It has been shown that mirs are independent predictios of outcome in patients with diffuse large b cell lymphoma treated with r-chop. Outcome in patients with dlbcl lymphoma treated with r-ch...
ORGANISM(S): Homo sapiens 
2015-02-20 | E-GEOD-40239 | biostudies-arrayexpress
UnknownBiotic and abiotic drivers of tree seedling recruitment across an alpine treeline ecotone.
Not available
S-EPMC6052039 | biostudies-literature
TranscriptomicsTranscription profiling of mouse hypomorphic for ATG16L1 (implicated in Crohns disease) protein expression reveals a key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
Susceptibility to Crohn's disease, a complex inflammatory disease involving the small intestine, is controlled by over 30 loci. One Crohn's disease risk allele is in ATG16L1, a gene homologous to the essential yeast autophagy gene ATG16 (ref. 2). It is not known how ATG16L1 or autophagy contributes ...
ORGANISM(S): Mus musculus 
2008-11-15 | E-GEOD-13512 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of TLR4 pathways in a murine model of chronic pulmonary inflammation and carcinogenesis
Toll like receptor 4 (TLR4), an innate immunity gene, is involved in responses to several pulmonary agonists including endotoxin (LPS; Poltorak et al.,1998), ozone (O3 ,Kleeberger et. al., 2001), Pseudomonas aeruginosa (Faure et al, 2004), and hyperoxia (Zhang et al, 2005). TLR4 appears to partially...
ORGANISM(S): Mus musculus 
2009-12-12 | E-GEOD-8504 | biostudies-arrayexpress
TranscriptomicsIn vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons
Huntington’s disease (HD), caused by a CAG repeat expansion in the huntingtin (HTT) gene, is characterized by abnormal protein aggregates and motor and cognitive dysfunction. Htt protein is ubiquitously expressed, but the striatal medium spiny neuron (MSN) is most susceptible to neuronal dysfunctio...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-25232 | biostudies-arrayexpress
TranscriptomicsHost cell-free growth of the Q fever bacterium Coxiella burnetii
The inability to propagate obligate intracellular pathogens under axenic (host cell-free) culture conditions imposes severe experimental constraints that have negatively impacted progress in understanding pathogen virulence and disease mechanisms. Coxiella burnetii, the causative agent of human Q (Q...
ORGANISM(S): Coxiella burnetii 
2010-06-20 | E-GEOD-13338 | biostudies-arrayexpress
UnknownAccelarated immune ageing is associated with COVID-19 disease severity.
Not available
S-EPMC10782727 | biostudies-literature
UnknownImpact of COVID-19 in patients on active melanoma therapy and with history of melanoma.
Not available
S-EPMC10033295 | biostudies-literature
UnknownClinical impact of COVID-19 on patients with cancer (CCC19): a cohort study.
Not available
S-EPMC7255743 | biostudies-literature
UnknownGlucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment.
Not available
S-EPMC9616982 | biostudies-literature
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