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TranscriptomicsTranscription profiling time series of human skeletal muscle samples from metabolic syndrome patients following defined exercise (STRRIDE study)
STRRIDE is an exercise intervention study of different doses and intensities in overweight women and men with the metabolic syndrome. We profiled biopsies from 3 female and 3 male STRRIDE subjects in the “high” exercise group (2,200 kCal/wk). Muscle biopsies were profiled at entry (0h), and afte...
ORGANISM(S): Homo sapiens 
2007-08-02 | E-GEOD-1295 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rats in a long-term Clofibric acid study
F344 rats were divided into 4 groups: vehicle control, DEN, DEN+CLO and CLO. After one week of basal diet, rats belonging to the groups DEN and DEN+CLO underwent intraperitoneal injection of DEN (30mg/kg body weight) dissolved in NaCl 9‰. The two other groups were injected with NaCl 9‰ alone. At...
ORGANISM(S): Rattus norvegicus 
2008-06-19 | E-GEOD-2216 | biostudies-arrayexpress
UnknownImpact of the addition of carboplatin and/or bevacizumab to neoadjuvant once-per-week paclitaxel followed by dose-dense doxorubicin and cyclophosphamide on pathologic complete response rates in stage II to III triple-negative breast cancer: CALGB 40603 (Alliance).
Not available
S-EPMC4268249 | biostudies-literature
TranscriptomicsResponse of multiple genes to a chronic dose of corticosteroids in rat muscles
Synthetic glucocorticoids are used therapeutically for a variety of conditions. Both the efficacy and toxicity of corticosteroids arise from their pharmacologically exaggerated effects on target and non-target tissues. For example, beneficial effects deriving from inhibition of the immune system are...
ORGANISM(S): Rattus norvegicus 
2006-06-19 | E-GEOD-5101 | biostudies-arrayexpress
GenomicsDeep sequencing reveals increased DNA methylation in chronic rat epilepsy (MBD-seq)
Explore DNA methylation in chronic epilepsy and its relationship to gene expression. Examination of methylation changes in pilocarpine-treated rats compared to controls and pilocarpine-treated rats on a ketogenic diet.
ORGANISM(S): Rattus norvegicus 
2013-09-09 | E-GEOD-50077 | biostudies-arrayexpress
ProteomicsAutoantibodies are abundant in all human sera: a demographic characterization via protein microarrays
Human serum samples were probed onto human protein microarrays in order to ascertain the number and diversity of naturally ocurring self-reactive IgG autoantibodies. In the study presented here, 166 human serum samples were probed onto human protein microarrays in order to identify self-reactive IgG...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-39087 | biostudies-arrayexpress
TranscriptomicsDeep sequencing reveals increased DNA methylation in chronic rat epilepsy (mRNA-seq)
Explore DNA methylation in chronic epilepsy and its relationship to gene expression. Examination of expression changes in pilocarpine-treated rats compared to controls and pilocarpine-treated rats on a ketogenic diet.
ORGANISM(S): Rattus norvegicus 
2013-09-09 | E-GEOD-50079 | biostudies-arrayexpress
TranscriptomicsEnvironmentally Induced Epigenetic Transgenerational Inheritance of Ovarian Disease [NimbleGen]
The actions of environmental toxicants and relevant mixtures in promoting the epigenetic transgenerational inheritance of ovarian disease was investigated with the use of a fungicide, a pesticide mixture, a plastic mixture, dioxin and a hydrocarbon mixture. After transient exposure of an F0 gestatin...
ORGANISM(S): Rattus norvegicus 
2014-07-17 | E-GEOD-59277 | biostudies-arrayexpress
TranscriptomicsGene Bionetworks that Regulate Ovarian Primordial Follicle Assembly
Primordial follicle assembly is the process by which ovarian primordial follicles are formed. During follicle assembly oocyte nests break down and a layer of pre-granulosa cells surrounds individual oocytes to form primordial follicles. The pool of primordial follicles formed is the source of oocy...
ORGANISM(S): Rattus norvegicus 
2013-01-15 | E-GEOD-43464 | biostudies-arrayexpress
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