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Renal ischemia reperfusion injury (I/R) has great clinical relevance and many treatments and hospitalizations are associated with this pathological process. Animal models are widely used in the development of kidney I/R studies and numerous papers have been published in this field in recent years su...
ORGANISM(S): Rattus norvegicus 
The main objectives were to validate the DNA array technology and establish the degree of correlation between any compound-induced effects on gene expression with those at the level of histological examination.
ORGANISM(S): Rattus norvegicus 
Efflux pumps are a significant challenge for the development of new antibacterial agents. Overcoming efflux requires an in-depth understanding of efflux pump functions, substrate specificities, and the development of inhibitors. However, the complexities of drug efflux networks have limited such stu...
ORGANISM(S): Escherichia coli 
2022-08-31 | PXD033975 | Pride
Copy number variation in two SJL sub-strains of an experimental autoimmune encephalomyelitis (EAE) rodent model of Multiple Sclerosis (MS)
ORGANISM(S): Mus musculus 
The area postrema (AP) is a sensory circumventricular organ characterised by extensive fenestrated vasculature and neurons which are capable of detecting circulating signals of osmotic, cardiovascular, immune and metabolic status. The AP can communicate these messages via efferent projections to bra...
ORGANISM(S): Rattus norvegicus 
The aim of this study was to identify alterations associated with diabetes-induced functional dysregulation of the retina and the effects of chronic insulin therapy. Transcriptional profiling through microarray analysis was analyzed to find mRNA targets of interest in diabetic samples, as well as i...
ORGANISM(S): Rattus norvegicus 
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