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TranscriptomicsMonkeypox and Vaccinia infection of cultured human cells
We analyzed effects of monkeypox (MPX) and vaccinia (VAC) infection on cultured human cells. Our custom-designed arrays contain >18,000 human genes as well as genes for each open reading frame of MPX and VAC. A reference experiement design type is where all samples are compared to a common referenc...
ORGANISM(S): Homo sapiens 
2008-07-17 | E-GEOD-11234 | biostudies-arrayexpress
TranscriptomicsStunned silence: gene expression programs in human cells infected with Monkeypox or Vaccinia virus
Three experiments, corresponding to the three figures in the article, are represented in this set. Each experiment was an ex vivo treatment time course as described in the paper. For each of the experiments, mRNA was isolated at the indicated time points, cDNA was directly prepared by reverse transc...
ORGANISM(S): Homo sapiens 
2011-04-14 | E-GEOD-24125 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat resistance artery in 2 models of hypertension
We investigated morphometric structure and gene expression by microarray analysis in a small diameter artery, branch of the saphenous artery (a resistance artery), in representative models of renin-angiotensin system (RAS)-dependent and glucocorticoid hypertension, using the spontaneously hypertensi...
ORGANISM(S): Rattus norvegicus 
2008-06-15 | E-GEOD-8051 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat testis aafter acute antibody mediated FSH suppression
To unravel the genes that underpin the effects of FSH on spermatogenesis, testicular gene expression was compared in juvenile rats after FSH suppression to littermate controls. Based on existing data, it is apparent that the dominant function of FSH shifts between 9 and 18 day postpartum (dpp) duri...
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-10293 | biostudies-arrayexpress
MetabolomicsDirect on-swab metabolic profiling of vaginal microbiome:host interactions during pregnancy and preterm birth

The pregnancy vaginal microbiome contributes to risk of preterm birth, the primary cause of death in children under 5 years of age. Here we describe direct on-swab metabolic profiling by Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) for sample preparation-free characterisation of...

2021-09-23 | MTBLS717 | MetaboLights
TranscriptomicsThe identification of putative circulating miRNA biomarkers of Thioacetamide-induced hepatotoxicity.
The Thioacetamide-treated rat was first identified as a model of hepatotoxicity by Gupta in 1956 and is now well-established, not least because the histopathogical output closely mimics that seen in humans with chronic liver disease. Acute treatment of rats with Thioacetamide causes pronounced necro...
ORGANISM(S): Rattus norvegicus 
2014-03-14 | E-GEOD-55885 | biostudies-arrayexpress
UnknownGenetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort.
Not available
S-EPMC9633436 | biostudies-literature
TranscriptomicsTranscription profiling of time series of C.elegans mutants and wild type
This series of samples comprises multiple early embryonic time courses for C. elegans. Time courses consisting of 10 time points each for 4 different genotypes are included: wild-type (strain N2 grown on E. coli strain OP50), pie-1(zu154) (progeny of homozygous mutant mothers [Unc] of strain JJ532 g...
ORGANISM(S): Caenorhabditis elegans 
2007-07-31 | E-GEOD-2180 | biostudies-arrayexpress
ProteomicsThermal Proteome Profiling Analysis of Targets of NSC59984 in ESO26-R248W Cells
Thermal proteome profiling analysis of ESO26-R248W esophageal adenocarcinoma cells treated with NSC59984 to identify targets of the inhibitor. Experimental details can be found in the meta data file.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-07-18 | MSV000095372 | MassIVE
UnknownCost-Effectiveness of Treatments after Closed Extraarticular Distal Radius Fractures in Older Adults from the WRIST Clinical Trial.
Not available
S-EPMC7855198 | biostudies-literature
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