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GenomicsChIP-seq based genome wide profiling of the histone mark H3K27ac and transcription factor Nuclear Factor 1 (NFI) in a differentiating murine brown preadipocyte cell line (IBA)
ChIP sequencing was used to generate genome-wide maps of the histone mark H3K27ac during in vitro differentiation of a murine brown preadipocyte cell line (IBA) at five different time points, in two biological replicates: Day 0 (confluence), 2h (post induction), Day 1, Day 2 and Day 4 (mature brown ...
ORGANISM(S): Mus musculus 
2017-09-21 | E-MTAB-5159 | biostudies-arrayexpress
GenomicsJmjd3-mediated H3K27me3 dynamics orchestrate brown fat cell fate transition and regulate white fat plasticity
We performed ChIP-seq to chart genome-wide maps of H3K27me3 in brown preadipocytes and mature brown adipocytes. We observed a subset of brown fat-specific genes, but not common fat genes or white fat-specific genes, possess the H3K27me3 mark in preadipocytes, and this mark is erased in mature adipoc...
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-55469 | biostudies-arrayexpress
TranscriptomicsIdentification of differentially expressed miRNAs between mouse subcutaneous white adipose tissue (scWAT) and interscapular brown adipose tissue (iBAT)
To identify miRNAs differentially expressed among undifferentiated and differentiated brown and white adipocytes, we profiled miRNA expression of preadipocytes isolated from the stromal vascular fraction (SVF) of scWAT and iBAT, undifferentiated or differentiated into mature brown and white adipocyt...
ORGANISM(S): Mus musculus 
2026-05-01 | E-MTAB-15230 | biostudies-arrayexpress
TranscriptomicsAnalysis of transcript abundances in Ectocarpus life cycle mutants
The aim of this experiment was to compare transcript abundances in parthenotes (i.e. organisms derived by parthenogenetic development of gametes) of two life cycle mutants of the brown alga Ectocarpus siliculosus with transcript abundances in the wild type sporophyte and gametophyte generations. Thi...
ORGANISM(S): Ectocarpus siliculosus 
2012-01-14 | E-MTAB-485 | biostudies-arrayexpress
UnknownEpigenetic interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat.
Not available
S-EPMC8617140 | biostudies-literature
UnknownTemporary inhibition of positive phototaxis in emigratory population of  Nilaparvata lugens by mark-release-recapture.
Not available
S-EPMC6730993 | biostudies-literature
UnknownA pair of threonines mark ent-kaurene synthases for phytohormone biosynthesis.
Not available
S-EPMC7990685 | biostudies-literature
UnknownEstimating deer density and abundance using spatial mark-resight models with camera trap data.
Not available
S-EPMC9189690 | biostudies-literature
TranscriptomicsExpression data from Control or ShSuz12 rat Intestinal epithelial cells IEC-6
Polycomb-group proteins form multimeric protein complexes involved in transcriptional silencing. The Polycomb Repressive complex 2 (PRC2) contains the Suppressor of Zeste-12 protein (Suz12) and the histone methyltransferase Enhancer of Zeste protein-2 (Ezh2). This complex, catalyzing the di- and tri...
ORGANISM(S): Rattus norvegicus 
2014-08-02 | E-GEOD-60003 | biostudies-arrayexpress
GenomicsNotch1-driven epigenetic changes in a mouse model of T cell Acute Lymphoblastic Leukemia (T-ALL)
T-cell acute lymphoblastic leukemia (T-ALL) is an immature hematopoietic malignancy driven mainly by oncogenic activation of NOTCH1 signaling. In this study we used a mouse model of T-ALL through the overexpression of the intarcellular transcriptionally active part of Notch1 (N1-IC). This model fait...
ORGANISM(S): Mus musculus 
2012-01-10 | E-GEOD-34954 | biostudies-arrayexpress
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