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TranscriptomicsGlobal effects of the CSR-1 RNA interference pathway on transcriptional landscape
Argonaute proteins and their small RNA co-factors short interfering RNAs (siRNAs) are known to inhibit gene expression at the transcriptional and post-transcriptional levels. In Caenorhabditis elegans, the Argonaute CSR-1 binds thousands of endogenous siRNAs (endo-siRNAs) antisense to germline trans...
ORGANISM(S): Caenorhabditis elegans 
2014-02-28 | E-GEOD-49946 | biostudies-arrayexpress
TranscriptomicsZFP-1(AF10)/DOT-1 Complex Opposes H2B Ubiquitination to Reduce Pol II Transcription
Inhibition of transcriptional elongation plays an important role in gene regulation in metazoans, including C. elegans, which lacks Negative Elongation Factor homologs. Here we combine genomic and biochemical approaches to dissect a novel role of C. elegans AF10 homolog, ZFP-1, in transcriptional c...
ORGANISM(S): Caenorhabditis elegans 
2013-07-05 | E-GEOD-47132 | biostudies-arrayexpress
GenomicsHuman RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors.
RNA polymerase (Pol) III transcribes many noncoding RNAs (for example, transfer RNAs) important for translational capacity and other functions. We localized Pol III, alternative TFIIIB complexes (BRF1 or BRF2) and TFIIIC in HeLa cells to determine the Pol III transcriptome, define gene classes and r...
ORGANISM(S): Homo sapiens 
2010-04-14 | E-GEOD-20309 | biostudies-arrayexpress
MetabolomicsProfiles of phenolic secondary metabolites in plants of barley (Hordeum vulgare L.)
Secondary metabolites are frequently involved in mechanisms of the plant tolerance to environmental stresses. Determining metabolic biomarkers for drought tolerance may be a useful implementation in increasing and stabilizing crop plant productivity. The most accurate and fast tool for this purpose ...
2014-11-20 | MTBLS52 | MetaboLights
UnknownInfected pancreatic necrosis: outcomes and clinical predictors of mortality. A post hoc analysis of the MANCTRA-1 international study.
Not available
S-EPMC10005914 | biostudies-literature
UnknownTiming of Cholecystectomy After Moderate and Severe Acute Biliary Pancreatitis.
Not available
S-EPMC10448376 | biostudies-literature
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