Sort   by:  
 Page size 
UnknownThe IAP family member BRUCE regulates autophagosome-lysosome fusion.
Not available
S-EPMC5807552 | biostudies-literature
TranscriptomicsRole of Apollon in human melanoma resistance to anti-tumor agents that activate the intrinsic or the extrinsic apoptosis pathways
PURPOSE: To assess the role of Apollon in melanoma resistance to intrinsic and extrinsic pathways of apoptosis and to identify strategies to reduce its expression. EXPERIMENTAL DESIGN: Expression of Apollon was assessed in melanoma cell lines and in surgical specimens.Gene expression profiling, m...
ORGANISM(S): Homo sapiens 
2012-07-10 | E-GEOD-34686 | biostudies-arrayexpress
ProteomicsEssential requirement for IER3IP1 in B cell development
In a forward genetic screen of mice with N-ethyl-N-nitrosourea (ENU)-induced mutations for aberrant immune function, we identified animals with low percentages of B220+ cells in the peripheral blood. The causative mutation was in Ier3ip1, encoding immediate early response 3 interacting protein 1 (IE...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-01-09 | MSV000091025 | MassIVE
MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
UnknownRadiosynthesis of microtubule-targeted theranostic methyl N-[5-(3'-radiohalobenzoyl)-1H-benzimidazol-2-yl]carbamates.
Not available
S-EPMC6377332 | biostudies-literature
TranscriptomicsTranscription profiling of Drosophila developmental time series
Michelle N. Arbeitman, Eileen E. M. Furlong, Farhad Imam, Eric Johnson, Brian H. Null, Bruce S. Baker, Mark A. Krasnow, Matthew P. Scott, Ronald W. Davis and Kevin P. White. Gene Expression During the Life Cycle of Drosophila melanogaster, Science, 297: 2270-2275, 2002. This work can be accessed fro...
ORGANISM(S): Drosophila melanogaster 
2004-11-06 | E-FLYC-6 | biostudies-arrayexpress
TranscriptomicsTrichuris muris infection drives cell-intrinsic IL4R alpha independent large intestinal RELMα+ macrophages.
The RELMα+ macrophage phenotype associates with the presence of anti-inflammatory macrophages and work in other model systems has demonstrated that the balance of pro-inflammatory and anti-inflammatory macrophages is critically important in enabling the resolution of inflammation. Moreover, in the c...
ORGANISM(S): Mus musculus 
2021-11-15 | E-MTAB-10501 | biostudies-arrayexpress
UnknownPSI-SMALP, a Detergent-free Cyanobacterial Photosystem I, Reveals Faster Femtosecond Photochemistry.
Not available
S-EPMC6976803 | biostudies-literature
TranscriptomicsArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
RELEVANCE: Smith-Lemli-Opitz syndrome (SLOS) is a human disease caused by mutations in the gene coding for the enzyme DHCR7 (7-dehydrocholesterol (7DHC) reductase), which catalyzes the final step of cholesterol biosynthesis. Accumulated 7DHC in tissues and body fluids of SLOS patients gives rise t...
ORGANISM(S): Mus musculus 
2021-03-20 | E-MTAB-10055 | biostudies-arrayexpress
UnknownPolymorphisms within the adenosine receptor 2a gene are associated with adverse events in RA patients treated with MTX.
Not available
S-EPMC2468887 | biostudies-literature
Sort   by:  
 Page size