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TranscriptomicsGene expression profiling of mouse splenic Dendritic cells subsets
We describe a novel subset of CD8+ DCs in lymphoid organs of naïve mice characterized by expression of the CX3CR1 chemokine receptor. CX3CR1+CD8+ DCs lack hallmarks of classical CD8+ DCs, including IL12 secretion, the capacity to cross-present antigen and their developmental independence of the tran...
ORGANISM(S): Mus musculus 
2010-07-28 | E-GEOD-23212 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Foxp3- CD25- regulatory T cells
The concept of immune regulation/suppression has been well-established. With thymus-derived CD4 CD25 regulatory T (TR) cells, it became clear that a variety of additional peripherally induced TR cells play vital roles in protection from many harmful immune responses including intestinal inflammatio...
ORGANISM(S): Mus musculus 
2008-10-25 | E-GEOD-12506 | biostudies-arrayexpress
TranscriptomicsIdentification of FOXP3-dependent transcripts in human FOXP3 expressing Jurkat T cells
The transcription factor (TF) Forkhead Box P3 (FOXP3) is constitutively expressed in high levels in natural occurring CD4+CD25+ regulatory T cells (nTreg) and is not only the most accepted marker for that cell population, but is considered lineage determinative. Chromatin immunoprecipitation (ChIP) ...
ORGANISM(S): Homo sapiens 
2012-11-26 | E-GEOD-37253 | biostudies-arrayexpress
TranscriptomicsFOXP3 binding sites in promoter regions of human Jurkat T cells
The transcription factor (TF) Forkhead Box P3 (FOXP3) is constitutively expressed in high levels in natural occurring CD4+CD25+ regulatory T cells (nTreg) and is not only the most accepted marker for that cell population, but is considered lineage determinative. Chromatin immunoprecipitation (ChIP) ...
ORGANISM(S): Homo sapiens 
2012-11-26 | E-GEOD-37252 | biostudies-arrayexpress
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