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Genomicsena-DATASET-GILD-07-06-2019-00:26:08:971-10 - samples
Deep sequencing of viral samples (average ~9,000x coverage) from patients chronically infected with Hepatitis B (HBV). Whole HBV genome sequencing of 1467 patients (1102 in discovery and 365 in validation cohort) chronically infected with HBV at baseline. The patient population contained HBV genot...
EGAD00001005075 | EGA
GenomicsLarge-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients
Despite the high global prevalence of chronic hepatitis B (CHB) infection, datasets covering the whole hepatitis B viral genome from large patient cohorts are lacking, greatly limiting our understanding of the viral genetic factors involved in this deadly disease. We performed deep sequencing of vir...
EGAS00001003689 | EGA
GenomicsDAC for hepatitis B analysis
Data Access Committee EGAC00001001228
EGAC00001001228 | EGA
GenomicsItalian Primary Biliary Cirrhosis Study

A Genome-wide association study of primary biliary cirrhosis (PBC) with an Italian cohort and loci meeting suggestive criteria were confirmed using a replication dataset from a previous Canadian study. The results confirmed associations for IL12A, IL12RB2, and HLA (peak between DQA1 and DQB1) and...

phs000444.v1.p1 | EGA
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