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TranscriptomicsTranscription profiling of fission yeast SAGA mutants shows that the SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8
The SAGA complex is a conserved multifunctional coactivator known to play broad roles in eukaryotic transcription. To gain new insights into its functions, we have performed biochemical and genetic analyses of SAGA in the fission yeast, Schizosaccharomyces pombe. Purification of the S. pombe SAGA ...
ORGANISM(S): Schizosaccharomyces pombe 
2008-11-19 | E-MTAB-53 | biostudies-arrayexpress
UnknownEfficacy and safety of front-line treatment regimens for Waldenstrom macroglobulinaemia: a systematic review and meta-analysis.
Not available
S-EPMC10485051 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation of fission yeast to determine Yox1 and cdc10 transcription factor binding sites
Transcription profiling of fission yeast /yox1/ deletion and genome wide location analysis of Yox1p and Cdc10p transcription factors reveal a negative feedback interaction: /yox1 /is transcriptionally activated by MBF, and Yox1p in turn transcriptionally represses the MBF target genes (including /yo...
ORGANISM(S): Schizosaccharomyces pombe 
2009-08-25 | E-TABM-647 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast strains identifies widespread requirement for SWI/SNF and RSC on transcription
SWI/SNF chromatin remodeling complexes play critical roles in transcription and other chromatin-related processes. The analysis of the two members of this class in Saccharomyces cerevisiae, SWI/SNF and RSC, has heavily contributed to our understanding of these complexes. To understand the in vivo ...
ORGANISM(S): Schizosaccharomyces pombe 
2008-06-13 | E-MTAB-31 | biostudies-arrayexpress
TranscriptomicsTranslation profiling of Schizosaccharomyces pombe size separated polysome fractions provides data on average numbers of associated ribosomes for most transcripts
To obtain translational profiles for all mRNAs, polysome preparations are separated according to their size using a sucrose gradient and the mRNAs in each fraction are identified and quantified with DNA microarrays. Starting with exponentially growing cells, we analyzed 12 polysome fractions using D...
ORGANISM(S): Schizosaccharomyces pombe 
2007-03-22 | E-TABM-222 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Salmonella enterica (I) serovar Typhi Ty2 wild type and ompR null strains in a strand-specific manner
Analysis of transcriptome in a strand-specific manner to further refine previous genome annotation; RNA-seq was also combined with microarray and proteome analysis to further define the S. Typhi ompR regulon and identify novel ompR regulated transcripts.
ORGANISM(S): Salmonella enterica 
2009-03-03 | E-TABM-644 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast wild type and yox1 mutant strains
Transcription profiling of fission yeast /yox1/ deletion and genome wide location analysis of Yox1p and Cdc10p transcription factors reveal a negative feedback interaction: /yox1 /is transcriptionally activated by MBF, and Yox1p in turn transcriptionally represses the MBF target genes (including /yo...
ORGANISM(S): Schizosaccharomyces pombe 
2009-08-20 | E-TABM-646 | biostudies-arrayexpress
no omics definedA coordintate global control over cellular transcription
Although much is known about the regulation of eukaryotic transcription, the global controls which determine rates of total transcription within a cell are not well understood. We have investigated the effects that the DNA to protein ratio has on both total cellular transcription and the transcripti...
ORGANISM(S): Schizosaccharomyces pombe 
2011-09-23 | E-TABM-1075 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation to measure RNA polymerase II occupancy in fission yeast
The relative amount of RNA polymerase II (Pol II) associated with a given ORF provides an estimate for transcriptional efficiency. We therefore established a systematic approach to measure Pol II occupancy using chromatin immunoprecipitation followed by analysis on microarrays
ORGANISM(S): Schizosaccharomyces pombe 
2007-03-22 | E-TABM-219 | biostudies-arrayexpress
UnknownResponse-adapted zanubrutinib and tislelizumab as a potential strategy to enhance CD19 CAR T-cell therapy in relapsed/refractory large B-cell lymphoma: A retrospective observational study.
Not available
S-EPMC12017895 | biostudies-literature
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