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GenomicsBRD4 dynamics reveal novel acrosome-dependent chromatin reorganization during post-meiotic mammalian sperm development
During the post-meiotic phase of spermatogenesis, transcription is progressively repressed as the nuclei of haploid spermatids are compacted through a dramatic chromatin reorganization involving hyper-acetylation and replacement of most histones with sperm-specific protamines. Although BRDT has been...
ORGANISM(S): Mus musculus 
2015-03-06 | E-GEOD-56526 | biostudies-arrayexpress
TranscriptomicsLevator Ani Satellite Cells (LASCs) treated with Nonsteroidal Androgen Receptor Agonist (NARA)
High regenerative capacity of adult skeletal muscle relies on a self-renewing depot of adult stem cells, termed muscle satellite cells (MSCs). A novel MSC line was isolated from the rat levator ani muscle and termed Levator Ani Satellite Cells (LASCs). Androgen, a known mediator of overall body com...
ORGANISM(S): Rattus norvegicus 
2014-11-20 | E-GEOD-63489 | biostudies-arrayexpress
TranscriptomicsExpression gene (angiocrine) profile of various activated endothelial cells
Endothelial cells were transduced with different genes modulating signaling pathways and compared to GFP transduced control group to identify changes in the expression of the angiocrine factors. The experiment compared endothelial genetic changes upon Akt, MAP kinase and PymT activation.
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-24093 | biostudies-arrayexpress
UnknownDevelopment and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair.
Not available
S-EPMC12267650 | biostudies-literature
UnknownDevelopment and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair.
Not available
S-EPMC11429686 | biostudies-literature
UnknownExploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database.
Not available
S-EPMC12579199 | biostudies-literature
UnknownAdd-On Treatment With Zilebesiran for Inadequately Controlled Hypertension: The KARDIA-2 Randomized Clinical Trial.
Not available
S-EPMC12120674 | biostudies-literature
UnknownClopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
Not available
S-EPMC6193486 | biostudies-literature
UnknownLong-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial.
Not available
S-EPMC3596060 | biostudies-literature
UnknownEnhancing cognitive performance prediction by white matter hyperintensity connectivity assessment.
Not available
S-EPMC11629703 | biostudies-literature
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