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TranscriptomicsMolecular Profiling of Breast Cancer Cells after Gemcitabine exposure
Human breast cancer cell lines were exposed to IC50 gemcitabine (Gemzar) for 24 and 48 hours. RNA was extracted, amplified and hibridized onto Oncochip microarray slides. Human breast carcinoma cell lines MCF7 and MDA-MB-231 were cultured in DMEM with Glutamax-1, supplemented with 10% fetal bovine s...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-4937 | biostudies-arrayexpress
TranscriptomicsSynergy between plasminogen activator inhibitor-1 and Snail in tumoral migration
Snail, a family of transcriptional repressors implicated in cell movement, has been correlated with tumour invasivity. The Plasminogen Activation system (PAs), including urokinase (uPA), its receptor (uPAR), and its inhibitor (PAI-1), also plays a key role in cancer invasion and metastasis, either t...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-10395 | biostudies-arrayexpress
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