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TranscriptomicsGenome-wide microRNA expression analysis of clear cell Renal Cell Carcinoma by next generation deep sequencing
MicroRNAs (miRNAs), non-coding RNAs regulating gene expression, are frequently aberrantly expressed in human cancers. Next-generation deep sequencing technology enables genome-wide expression profiling of known miRNAs and discovery of novel miRNAs at unprecedented quantitative and qualitative accura...
ORGANISM(S): Homo sapiens 
2012-06-21 | E-GEOD-37616 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profiling in embryonic chicken heart
MicroRNAs are small non-coding RNA transcripts that regulate post-transcriptional gene expression. The millions of short sequence reads generated by next generation sequencing technologies make this technique explicitly suitable for profiling of known and novel microRNAs. A modification to the small...
ORGANISM(S): Gallus gallus 
2010-12-21 | E-GEOD-20757 | biostudies-arrayexpress
TranscriptomicsExpression profiling of the forming atrioventricular node using a novel Tbx3-based node-specific transgenic reporter
The atrioventricular (AV) node is a recurrent source of potentially life-threatening arrhythmias. Nevertheless, limited data are available on its developmental control or molecular phenotype. We used a novel AV node-specific reporter mouse to gain insight into the gene programs determining the forma...
ORGANISM(S): Mus musculus 
2009-06-02 | E-GEOD-13614 | biostudies-arrayexpress
TranscriptomicsDivergent gene-expression profiles between proepicardium and epicardium differentiation
The HH16/17 chicken proepicardium (PE) gives rise to the embryonic epicardium (Epi) which significantly contributes formation of the coronary vasculature during cardiac development. In contrast to explanted Epi cells, explanted PE cells can undergo differentiation into a cardiac myocyte phenotype. I...
ORGANISM(S): Gallus gallus 
2010-12-21 | E-GEOD-13923 | biostudies-arrayexpress
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