A non-targeted metabolomics-based approach is presented that enables the study of pathways in response to drug action with the aim of defining the mode of action of trypanocides. Eflornithine, a polyamine pathway inhibitor, and nifurtimox, whose mode of action involves its metabolic activation, are ...
Kerkhoven2013 - Glycolysis in T.brucei - MODEL A
There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. Model A ( BIOMD0000000513
) is the model developed originally by Achar et al. (2012) ( BIOMD0000000428
), which des...
Kerkhoven2013 - Glycolysis and Pentose Phosphate Pathway in T.brucei - MODEL B
There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. Model A ( BIOMD0000000513
) is the model developed originally by Achar et al. (2012) ( BIOMD00000...
Kerkhoven2013 - Glycolysis and Pentose Phosphate Pathway in T.brucei - MODEL C in fructose medium (with glucosomal ribokinase)
There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. Model A ( BIOMD0000000513
) is the model developed origi...
Kerkhoven2013 - Glycolysis and Pentose Phosphate Pathway in T.brucei - MODEL D in fructose medium (with ATP:ADP antiporter)
There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. Model A ( BIOMD0000000513
) is the model developed original...
Kerkhoven2013 - Glycolysis and Pentose Phosphate Pathway in T.brucei -MODEL C (with glucosomal ribokinase)
There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. Model A ( BIOMD0000000513
) is the model developed originally by Achar et al...
Kerkhoven2013 - Glycolysis and Pentose Phosphate Pathway in T.brucei - MODEL D (with ATP:ADP antiporter)
There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. Model A ( BIOMD0000000513
) is the model developed originally by Achar et al. ...
