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MetabolomicsUntargeted Metabolomics Reveals a Lack Of Synergy between Nifurtimox and Eflornithine against Trypanosoma brucei
A non-targeted metabolomics-based approach is presented that enables the study of pathways in response to drug action with the aim of defining the mode of action of trypanocides. Eflornithine, a polyamine pathway inhibitor, and nifurtimox, whose mode of action involves its metabolic activation, are ...
2017-06-07 | MTBLS459 | MetaboLights
TranscriptomicsGeoChip 5 microarray data to determine gene activity in microbially influenced corrosion and associated samples from Shoreham Harbour, U.K.
Samples collect to investigate the gene activity from microbial populations in marine steel corrosion, and to compare with gene activity in water and bed sediment samples from the surrounding area. The study was undertaken to (1) investigate mechanisms of microbially influenced corrosion (MIC) of ma...
ORGANISM(S): mixed sample 
2019-11-01 | E-MTAB-8364 | biostudies-arrayexpress
UnknownComparable Disease Severity by Influenza Virus Subtype in the Acute Respiratory Infection Consortium Natural History Study.
Not available
S-EPMC7427663 | biostudies-literature
UnknownEffects of human immunodeficiency virus status on symptom severity in influenza-like illness in an otherwise healthy adult outpatient cohort.
Not available
S-EPMC8319060 | biostudies-literature
MetabolomicsAmphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism, lipid transport and oxidative stress response

Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen independent lines of Leishmania mexicana and one L. infantum line were selected for resistance to either amphotericin B or the related polyene antimicrobial, nystatin. Sterol profiling revealed tha...

2022-09-22 | MTBLS2744 | MetaboLights
UnknownSARS-CoV-2 variant replacement constrains vaccine-specific viral diversification.
Not available
S-EPMC11463026 | biostudies-literature
UnknownEstimating the Effect of Coronavirus Disease 2019 (COVID-19) Vaccination and Infection Variant on Post-COVID-19 Venous Thrombosis or Embolism Risk.
Not available
S-EPMC11530954 | biostudies-literature
Transcriptomicspamknight ovine abomasum
To address the protective mechanisms generated in animals on previous exposure to this parasite, using samples of abomasal mucosa collected pre- and post- challenge from animals of differing immune status in an experimental model of T. circumcincta infection.
ORGANISM(S): Ovis aries 
2011-05-20 | E-TABM-1150 | biostudies-arrayexpress
Transcriptomicspamknight ovine abomasum1
To address the protective mechanisms generated in animals on previous exposure to this parasite, using samples of abomasal mucosa collected pre- and post- challenge from animals of differing immune status in an experimental model of Teladorsagia circumcincta infection.
ORGANISM(S): Ovis aries 
2011-05-20 | E-TABM-1149 | biostudies-arrayexpress
UnknownPrecision Symptom Phenotyping Identifies Early Clinical and Proteomic Predictors of Distinct COVID-19 Sequelae.
Not available
S-EPMC12308661 | biostudies-literature
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