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TranscriptomicsIdentification of genes essential for Moraxella catarrhalis growth under iron-limiting conditions using Genomic Array Footprinting (GAF)
Iron-sequestration by the human host is a first line defense against respiratory pathogens like Moraxella catarrhalis, which consequently experiences a period of iron-starvation during colonization and infection. We determined the genetic requirements for M. catarrhalis growth during iron-starvation...
ORGANISM(S): Moraxella catarrhalis BBH18 
2013-06-06 | E-GEOD-41546 | biostudies-arrayexpress
TranscriptomicsIdentification of genes essential for Moraxella catarrhalis growth under iron-limiting conditions using Genomic Array Footprinting (GAF): Expression analysis of directed gene deletion mutants.
Iron-sequestration by the human host is a first line defense against respiratory pathogens like Moraxella catarrhalis, which consequently experiences a period of iron-starvation during colonization and infection. We determined the genetic requirements for M. catarrhalis growth during iron-starvation...
ORGANISM(S): Moraxella catarrhalis BBH18 
2013-06-06 | E-GEOD-41547 | biostudies-arrayexpress
TranscriptomicsGene expression of non-typeable Haemophilus influenzae strain R2866 and R2866Δ0112 mutant grown in supplemented brain-heart infusion medium for 4 hours
Gene expresison profiles of the R2866 WT and R2866Δ0112 mutant gorwn 4 hours in supplemented brain-heart infusion medium. This experiment was conducted to determine the effects of R2866_0112 gene deletion on overall gene expression profile. The results from this study are further discussed in: Mod...
ORGANISM(S): Haemophilus influenzae R2866 
2013-12-13 | E-GEOD-53287 | biostudies-arrayexpress
TranscriptomicsGene expression of non-typeable Haemophilus influenzae strain R2866 and R2866Δ0112 mutant grown in supplemented brain-heart infusion medium for 7 hours
Gene expresison profiles of the R2866 WT and R2866Δ0112 mutant gorwn 7 hours in supplemented brain-heart infusion medium. This experiment was conducted to determine the effects of R2866_0112 gene deletion on overall gene expression profile. The results from this study are further discussed in: Mod...
ORGANISM(S): Haemophilus influenzae R2866 
2013-12-13 | E-GEOD-53289 | biostudies-arrayexpress
TranscriptomicsGAF competence
We applied a novel negative selection strategy called genomic array footprinting (GAF) to identify genes required for genetic transformation of the gram-positive bacterium Streptococcus pneumoniae. Genome-wide mariner-transposon mutant libraries in S. pneumoniae strain R6 were challenged by transfor...
ORGANISM(S): Streptococcus pneumoniae R6 
2007-09-04 | E-GEOD-8362 | biostudies-arrayexpress
TranscriptomicsGenome-wide identification of Streptococcus pneumoniae genes essential for the development of experimental meningitis
We applied genomic array footprinting (GAF) in the search for genes of S. pneumoniae essential during the establishment and progression of experimental meningitis. Four libraries with a total of 6,000 independent TIGR4 marinerT7 transposon mutants were injected intra-cisternally in rabbits, and cere...
ORGANISM(S): Streptococcus pneumoniae 
2010-11-16 | E-GEOD-21729 | biostudies-arrayexpress
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